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Synergies produced in NANBIOSIS multiply the value of its services and allow its users to have results with faster and superior reliability due to proven experience of the scientists and technicians involved, says Jaume Veciana, Scientific Director of NANBIOSIS, in an interview at July 2016 CIBER-BBN Bulletin.

In this interview, Jaume Veciana assesses the functioning of this Singular Scientific-Technical Infrastructure and its contribution to research and anticipates some of the guidelines of the NANBIOSIS Strategic Plan 2017-2020, which includes a clear commitment to internationalization.

“The scientific-technical capabilities available at NANBIOSIS must be exploited without limitation to our country. Therefore we are clear that we must promote the activity of NANBIOSIS both academic and industrial sector in the European Union and other countries, either directly or in association with other similar organizations actions. Some such initiatives have already started but we believe it should be given further boost to internationalization. As an example we can mention the participation in the European project INFRAIA that aims to integrate regional and national research infrastructures existing in Europe under the Horizon 2020”

Professor Veciana also talks about NANOMOL, the research group coordinator of Unit 6 of NANBIOSIS, and the main applications of their findings in the fields of nanomedicine and biomaterials.

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Synergies produced in NANBIOSIS multiply the value of its services and allow its users to have results with faster and superior reliability due to proven experience of the scientists and technicians involved, says Jaume Veciana, Scientific Director of NANBIOSIS, in an interview at July 2016 CIBER-BBN Bulletin.
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Dr. Simó Schwartz, Scientific Director of Unit 20 of NANBIOSIS: appointed president of the European Society for Nanomedicine (ESNAM) and member of the executive board of the International Society of Nanomedicine (ISN).

The objectives of ESNAM are to promote nanomedicine research and facilitate the exchange of knowledge among its members (currently, about 800 members). According to Dr. Simó Schwartz “the dissemination of specialized infrastructure in nanomedicine, like NANBIOSIS, among members of the society and its utilities is also an object of ESNAM. This is intended to strengthen European technological capabilities, use, and improvement of clinical transfer”.

Society members represent different sectors of the scientific community: doctors, biologists, chemists, pharmacists, physical …. The technical office of the ESNAM in Barcelona is located in the Vall d’Hebron Hospital and is coordinated by Aida Castellanos, CIBER-BBN R&D+i Project Manager.

In addition, Dr. Schwartz has also been appointed a member of the executive board of the International Society of Nanomedicine (ISN), a newly established company that includes the American Association, Korean and European, ESNAM, among others. This entity will organize the 2nd year of summer in Barcelona Nanomedicine 2017, this year held in South Korea.

Dr. Simó Schwartz, Scientific Director of Unit 20 of NANBIOSIS: appointed president of the European Society for Nanomedicine (ESNAM) and member of the executive board of the International Society of Nanomedicine (ISN).
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Pablo Laguna and Jordi Aguilo, Scientific Directors of the Units 27 and 8 of NANBIOSIS participate in the European program Remote Assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS)

RADAR-CNS is an important European research program supported by the Innovative Medicines Initiative (IMI) focused to develop new ways of monitoring patients affected by major depression, epilepsy and multiple sclerosis, with the use of wearable technology and smart mobile phones.

This program brings together experts from various disciplines in clinical research, engineering, computer and data analysis, as well as health services. RADAR-CN aims to improve symptoms and quality of life of patients and treatment of these and other chronic diseases. This program is jointly led by King’s College London and the pharmaceutical company Janssen and is funded by the Innovative Medicines Initiative (a public-private agreement EFPIA and the European Union). RADAR-CNS involves 24 organizations in Europe and US, including CIBER through its thematic areas of Mental Health (CIBERSAM) and Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)

“In recent years, the quality and quantity of data that can be collected with the wearable technology and smart phones has increased a lot. The information generated with this large amount of data will help to improve clinical care by providing greater detail of the patient’s condition and prognosis of its evolution. Moreover, it will be possible to detect whether a patient is beginning to have problems before there is clinical evidence of it” says Dr. Jordi Aguilo, scientific coordinator of the Unit 8 of NANBIOSIS.

This huge generate data sets, suitable to be stored and treated so to retrieve the relevant information hidden in the data, frequently require computing systems and information systems of high performance. The Unit 27 of NANBIOSIS will be the platform in which this analysis will be performed.

Pablo Laguna and Jordi Aguilo, Scientific Directors of the Units 27 and 8 of NANBIOSIS participate in the European program Remote Assessment
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Elizabeth Engel, Scientific Coordinator of Unit 5 of NANBIOSIS: “Our research has opened the door to the regeneration of the nervous system by biomaterials”

The CIBER-BBN research group Biomaterials for Regenerative Therapies, which coordinates Unit 5 of NANBIOSIS develops various lines of research on biomaterials for regenerative therapies, especially focusing on the design and fabrication of scaffolds for tissue regeneration. They are working with polymers, hydrogels and compounds that can be manufactured using different techniques such as electrospinning to make 3D printing matrices or scaffolding. Applications are diverse, such as bone regeneration, neuronal, skin or cell therapy.

The group has recently presented the results of a project focused on the development of implants for the regeneration of nerve tissue with very promising results. The study opens the door to the possibility of regenerating the nervous system, since the capacity of cells to dedifferentiate is demonstrated and thus become capable of generating tissue cells. Moreover, these nanofibers scaffolds benefits vascularization (generation of new blood vessels) in the injured area, which promotes regeneration. The study has been shown in laboratory mouse and currently Dr. Alcantara (University of Barcelona), with whom the group is collaborating on this project since 6 years ago, is doing tests in rats to show that new neurons generated are functional.

The new prospects for medicine opened by this finding are very important: The first is the regenerative capacity of the brain. The second, biomaterials play a fundamental role in this regeneration and can open an important way for the development of biomedical devices that advance tissue regeneration using whose regulatory systems to market is much less complex than advanced therapies based cells and growth factors. 3D printing opens a new approach to fabricate this type of implants, as more porous structures can be printed to favor cell colonization and vascularization.

Elizabeth Engel, Scientific Coordinator of Unit 5 of NANBIOSIS: “Our research has opened the door to the regeneration of the nervous system by biomaterials”
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