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Posts on Jan 1970

FORUM “Intelligent Biomaterials and Biomedical Devices for Drug Delivery and Regenerative Medicine”

NANBIOSIS has organized a forum for researchers and companies that will take place on October 4 and 5 at the Jesús Usón Minimal Invasion Surgery Center (Carretera N-521, km 41,8 · 10071 Cáceres).

The theme of the Forum is INTELLIGENT BIOMATERIALS / FUNCTIONALIZATION AND BIOMEDICAL DEVICES FOR APPLICATIONS IN REGENERATIVE MEDICINE AND DRUG DELIVERY.

The forum is presented through 2 sessions:
• First session, Wednesday, October 4, afternoon (from 3:00 p.m.): Short interventions of the latest advances and developments in the lines of research developed by the groups and platforms of Nanbiosis and description of the needs and demands of industry in that area. The companies and groups that request it will be able to have about 10 ‘to present their lines of research and / or needs and demands in relation to the thematic of the forum.
• Second session, Thursday, October 5, morning (9:00 a.m. to 1:00 p.m.): Bilateral company-group / platform meetings to identify possible collaborations. These meetings will be pre-scheduled on request.

On the part of CIBER-BBN and the CCMIJU (partners of NANBIOSIS) will participate 10-12 groups of investigation experts in the matter.

If you are interested in participating, there are still some places that will be covered by a strict registration order. Registration is free. For this you can contact before September 22 with Eduard Farré (628.943.198, efarre@arvor-ing.com) or with Jesús Izco (679.490.537, jmizco@ciber-bbn.es).

In the following link you can consult the provisional agenda of the event: Agenda Forum NANBIOSIS Cáceres

 

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II MASTER ON ENDOSCOPY AND MINIMALLY INVASIVE SURGERY IN SMALL ANIMALS (CEyCMI). EXTRAORDINARY DEADLINE FOR ADMISSIONS

A new extraordinary deadline for admissions to the II MASTER ON ENDOSCOPY AND MINIMALLY INVASIVE SURGERY IN SMALL ANIMALS has been set up, from 1st to 14th September. It is organised in collaboration with the Extremadura University ant takes place in Jesús Usón Minimally Invasive Surgery Centre as affiliated entity, offering 60 ECTS-credits.Necessary requirements include having a Veterinary studies degree and a B1 English Certificate. The Master will be held during the academic calendar 2017-2018, according to the established program, that will promote the interaction with the students via an on-line training platform, the direct contact with professors and experts, as well as offering an open material repository.

The Master consists on 4 hands-on training sessions at the JUMISC’s, an external stage in one of our partners centre and the Master’s degree final project.

Further info: www.ccmijesususon.com/ceycmi2017

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Gold nanoparticles can activate drugs inside tumors

Jesus Santamaría, Scientific Director of Unit 9 of NANBIOSIS has participated in a study that shows the ability of gold nanoparticles to generate in situ potent anticancer drugs from inert molecules thanks to a mechanism of elimination of terminal chemical groups that nanometric gold is able to catalyze. Gold is ideal for this catalytic role due to its high biocompatibility.

These results, published in the journal Angewandte Chemie, offer new hope in the fight against cancer and have been obtained thanks to the collaboration of scientists of Unit 9 of NANBIOSIS and, Víctor Sebastián, Silvia Irusta and Jesús Santamaría, with researchers from the Center for Cancer Research at the University of Edinburgh, led by Dr. Unciti-Broceta.

The work reveals the possibility of carrying out catalysis in biological means using tiny particles of gold. These gold nanoparticles, camouflaged in a resin microcapsule implanted in the brain of a zebrafish, have succeeded in catalyzing a chemical reaction generating fluorescent compounds.

Significant practical importance

“The main problem of chemotherapy treatments are the side effects in various organs due to the toxicity of the molecules that are used to fight cancer. For this reason, alternative routes are explored from nanotechnology, for example, transporting drugs to the tumor using nanoparticles or alternative treatments to drugs, such as hyperthermia, elevation of local temperature, obtained with nanoparticles”, says Jesús Santamaría.

The conclusions of this work suggest a different way: the drug would be supplied to the patient in its inert form and only converted to the toxic form locally, thanks to the catalysis of the nanoparticles that a surgeon would implant in the tumor.

 

Article of reference

Pérez-López, A. M., Rubio-Ruiz, B., Sebastián, V., Hamilton, L., Adam, C., Bray, T. L., Irusta, S., Brennan, P. M., Lloyd-Jones, G. C., Sieger, D., Santamaría, J. and Unciti-Broceta, A. (2017). “Gold-Triggered Uncaging Chemistry in Living Systems”. Angew. Chem. Int. Ed.. doi:10.1002/anie.201708379

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