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U10. Drug Formulation

U10. Drug Formulation

U10-E36. Regemat 3D V1 Bioprinter

Regemat 3D V1 Bioprinting

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U10-S09. Characterization and development of pulmonar formulations (On-site&Remote) OUTSTANDING

Characterization and development of pulmonar formulations

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U10-S08. 3D bio-impression of scaffolding for regenerative medicine (On-site&Remote) OUTSTANDING

3D bio-impression of scaffolding for regenerative medicine

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U10-S9. Characterization and development of pulmonar formulations (On-site&Remote) OUTSTANDING

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U10-S8. 3D bio-impression of scaffolding for regenerative medicine (On-site&Remote) OUTSTANDING

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U10-E38 Equipment of biopharmaceutical characterization of pulmonary formulations with Breath Simulator and Alberta Idealised Throat (AIT)

Equipment of biopharmaceutical characterization of pulmonary formulations with Breath Simulator and Alberta Idealised Throat (AIT)

 

1) NGI Cascade Impactor: It’s an analytical tool for the development of inhalation products. It’s use for the testing of all inhalation formulations and devices: MDIs, DPIs, nebulizers and aerosol and nasal sprays. It’s the new “workhorse” of the pharmaceutical industry.

2) Alberta Idealised Throat (AIT): before entering the lungs, aerosols must traverse the mouth-throat. So it’s important to be able to mimic aerosol deposition and flow in the human mouth-throat when studying inhaled aerosols. The Alberta geometry has been shown to do a remarkable job of mimicking the aerosol and flow motion in the human mouth-throat and allow researchers examining  and testing aerosols inhaled orally.

3) Breath Simulator: are increasingly used in testing orally inhaled and nasal drug products (OINDPs) to replace existing constant flow conditions with breathing profiles more representative of conditions in vivo. It can be used for improved IVIVC applications, with real breath profiles generated in clinic.

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U10-E37. 3D Bioprinter

3D Bioprinting

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U10-E35 Confocal Microscopy Unit

Confocal Microscopy Unit

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New bioadhesive with 3D printing technique to improve pterygium surgery

Dr. José Luis Pedraz, head of Nanobiocel group and Scientific Director of Unit 10 of NANBIOSIS, participates in the public-private collaboration BIOTAPE project that will develop a new bioadhesive for its application in pterygium surgery to improve the currently used surgical techniques in the treatment of this eye disease that affects the conjunctiva and cornea.

The main cause of pterygium is the lack of lubrication of the eye by the tear film. This lack of lubrication may be due to various external factors such as excessive exposure to sunlight, harsh environmental conditions or even allergens, which causes dryness and subsequent irritation in that area. Pterygium grows in the form of fleshy mass on the cornea, being in these cases the application of surgery to extract it. So far the technique with better results is to place a graft of the conjunctiva of the eye itself in the place of removal of the pterygium, fixed by sutures or tissue adhesives.

In the BIOTAPE  project, 3D printing technique will be used to manufacture the new bioadhesive that will help reduce the current complications among which we can highlight the high rates of recurrence of the disease, surgical and post-surgical complications and the cosmetic result, not always satisfactory.

The new project, to be developed over the next three years, is funded with a budget of 513,000 euros by the Challenges-Collaboration program of the Ministry of Economy, Industry and Competitiveness and the participation of three Spanish companies (AJL OPHTALMIC, BRECA Health Care and Bilboftal-ICQO), the University of Miguel Hernández in Elche, CIBER-BBN and unit 10 of NANBIOSIS-ICTS.

Nanbiosis - New bioadhesive with 3D printing technique to improve pterygium surgeryLogo FEDER - Nanbiosis

“Promover el desarrollo tecnológico, la innovación y la investigación de calidad”

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U10-E34. Climate chambers with temperature and humidity control

Climate chambers are needed because our laboratory is able to carry out stability studies in climatic chambers under ICH conditions and with access to Good Laboratory Practice (GLP).

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