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U25. NMR: Biomedical Applications I

U25. NMR: Biomedical Applications I

U25-E10. Animal housing

Animal housing room and animal preparation area equipped with a vital constants monitoring system, 2 full sets of anesthesia equipment, water bath, infrared lamp, injection pump, etc.

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U25-E11. Software packages

Software packages for data acquisition and processing:

  • Paravision, Topspin and Amix.
  • Users will have access to the database of spectra of diffe¬rent substances for metabolomics through this ac¬cess http://sermn. uab.cat/wiki/doku.php?id=bbiorefcode. This database is installed in a SeRMN computer, fully accessible to facility users.
  • The AMIX software page (http://www.bruker-biospin.com/amix. html) contains more information about its different applications: analysis of mixtures, metabolomic stu-dies, etc.
  • Other packages include the INTERPRET decision-support system for human brain tumour diagnosis based on MRS and SpectraClassifier, for pattern recognition of in vivo MRS data single and multivoxel are developed and distributed through the platform (http://gabrmn.uab.es).
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U25-S01. NMR spectrometer 250MHZ robot/250MHZ auto/360MHZ/400MHZ (Onsite&Remote) OUTSTANDING

NMR experiments in high-resolution 1D and 2D structural characterization of molecules chemical origin (http://sct.uab.cat/sermn/en/content/chemical-structure)

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U25-S02. NMR spectrometer 500MHz/600MHz (Onsite&Remote) OUTSTANDING

NMR experiments in high-resolution 1D and 2D structural characterization of molecules chemical origin (http://sct.uab.cat/sermn/en/content/chemical-structure)

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U25-S03. NMR spectrometer 400 MHz with HRMAS/CPMAS probes (Onsite&Remote) OUTSTANDING

HRMAS (High Resolution Magic Angle Spinning) allows to perform high resolution NMR experiments at samples which are in an intermediate state between liquid and solid, so viscous or heterogeneous samples. (http://sct.uab.cat/sermn/en/content/hrmas)

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U25-S04. 500 MHz spectrometer HPLC-NMR(Onsite&Remote) OUTSTANDING

The technique HPLC-DAD-(SPE) -NMR/MS is suitable for the analysis of mixtures. Combining high-resolution liquid chromatography with detection techniques NMR spectroscopy, mass spectrometry (MS) and diode array detection (DAD). (http://sct.uab.cat/sermn/en/content/complex-mixtures)

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U25-S05. Preclinical horizontal spectrometer Biospec 7T (Onsite&Remote) OUTSTANDING

Non-invasive manner to record high-resolution MRI images, and do spectroscopy focused on biological samples, small animals or plants, and other materials (http://sct.uab.cat/sermn/en/content/magnetic-resonance-imaging-mri)

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U25-S06. Dynamic nuclear polarizer HyperSense® (Onsite&Remote) OUTSTANDING

Hyperpolarization of samples allows to work with highly polarized nuclear spins in solution, afording a considerable sensitivity gain (http://sct.uab.cat/sermn/en/content/dnp-0)

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U25-S07. Focused Microwave Fixation system (Onsite&Remote) OUTSTANDING

Use of the equipment for the fixation of living tissue

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U25-S08. NMR consultancy for processing and interpreting data (Onsite&Remote)

Technical and/or Scientific support for NMR design and data interpretartion

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