Francisco M. Sánchez-Margallo, Assistant Director of NANBIOSIS and Scientific Coordinator o NANBIOSIS U23. Assisted Reproduction, is co-author of the article “Mimicking physiological O2 tension in the female reproductive tract improves assisted reproduction outcomes in pig”, publish by the Journal Molecular human reproduction
The research has been carried out with the participation of the NANBIOSIS Assisted Reproduction Lab that has a 120 m2 laboratory, small animal surgery, clinical analysis support, etc. and it is featured with two intracitoplasmatic micromanipulation equipment of the latest generation with IMSI, Laser and Oosight system, embryo biopsy systems, vision systems of the mitotic spindle, with flow cabinets with stereo-microscopes and heated plates, incubators with different gasses systems, equipment and cryopreservation freeze gamete and embryo, among others
STUDY QUESTION:
Is O2 tension in the pig oviduct and uterus affected by the estrous cycle stage and the animal’s age, and can the outcome of in vitro embryo development be improved by mimicking these physiological values?
SUMMARY ANSWER:
O2 tension within the pig reproductive organs is affected by the animal’s age, and values close to those measured in vivo have a positive impact on embryo development and quality when used during IVF and embryo culture (EC).
Article of reference: doi: 10.1093/molehr/gay008