Located at the Research Center onNanoscience and Nanotechnology(CIN2), CSIC, at the campus of Universidad Autónoma de Barcelona (UAB) the Biodeposition Unit consists of a versatile and automated molecular printer that can dispense minute volumes of solutions (from atto to femtoliter volumes) on a wide variety of surfaces to create user-defined patterns of spots or lines with high spatial resolution. The system is suitable for the functionalization of biosensors with any kind of biomolecule, nanoparticles, graphene or other nanostructures,for surface patterning for cell culture, or for the preparation of micro/nanoarrays, among other applications. The laboratory also harbors a Surface Plasmon Resonance (SPR) service. The Unit is coordinated by Prof. LauraM. Lechuga, group leader from the Nanobiosensorsand Bioanalytical Applications Group (nanoB2A) at CIN2-CSIC.
The group Biosensors and bio-analytic applications, led by Laura Lechuga, coordinator of Unit 4 of NANBIOSIS, has developed a methodology through a nano-photonic sensor (known as bimodal waveguide interferometer) capable of quantifying, directly and mark-free, the different messenger RNA isoforms generated by alternative splicing. The expertise in biodeposition and biodetection systems of Lechuga’s group has permitted a thorough analytical study and optimization of the methodology, achieving not only total selectivity, but also excellent levels of sensitivity and reproducibility, and obtaining the lowest levels of detection in direct detection of messenger RNA isoforms generated by this mechanism without the need for PCR amplification (polymerase chain reaction). T[...]
On December 14th, the Physics Awards ceremony was held at the BBVA Foundation’s headquarters, organized by the Spanish Royal Society of Physics (RSEF) and the BBVA Foundation, that each year select the most relevant achievements of Spanish physics. On this occasion the achievements of nanoscience have been recognized and it has been highlighted the power of physics to expand the territory of the known universe and the role of scientists as a core element of social progress. Professor Laura Lechuga, Scientific Director of Unit 4 of NANBIOSIS received the Physics, Innovation and Technology Prize was the only woman awarded. Lechuga[...]
Laura M. Lechuga, Scientific Director of the Unit 4 of NANBIOSIS has won the Physics Prize of the Royal Spanish Society of Physics (RSEF) -Foundation BBVA 2016 in the form of Physics, Innovation and Technology, endowed with 8,000 euros. Physics Awards recognize this year to researchers who have revealed the potential of the “nanoworld” to create new materials and fight disease. The jury highlighted her “excellent track record as a scientist, technologist and innovative” in the field of biosensor devices. “Prof. Lechuga – emphasizes the jury- has managed to walk the path from idea to product with great success. Her[...]
The selection of the best Spanish researchers in 2016 is an initiative of the magazine QUO to disseminate the work of scientists. The jury formed by eight eminent scientists (Amils, Ainhoa Goni, Emilio Lora-Tamayo, Vladimir de Semir, Fernando Peláez, Antonio Calvo, Pilar López and Manuel Toharia, has chosen the twelve scientists of international prestige who will form the Spanish National Science 2016: – Pedro Cavadas, plastic surgeon specializing in transplants – Mariano Barbacid, a biochemist at the National Cancer Research Centre (CNIO) – Susana Marcos, director of the Institute of Optics ‘Daza Valdes’ CSIC – Alberto Ruiz Jimeno, founder of[...]
The peritonitis bacterial spontaneous is an infection of the fluid ascetic that has high incidence in cirrhotic patients and is associated with a high mortality. In such situation, a diagnosis early is essential for the survival of the patient. However, the identification of the causative pathogen of infection is based currently on cultivation methods that are slow and laborious. A research coordinated by the Group of Nanobiosensors and Bioanalytical applications of the CIBER-BBN, which coordinates Unit 4 of NANBIOSIS led by Laura Lechuga, has presented the development of a biosensor interferometric based in guides bimodal (BiMW), capable of identify and[...]
The group of Nano-biosensors and Bioanalytical applications of CIBER-BBN which coordinates Unit 4 of NANBIOSIS directed by Dr. Laura Lechuga, has led the final preparations of a technology with potential application in the early diagnosis of colorectal cancer, based in the detection of specific biomarkers in blood. The nanoplasmonic biosensor based on LSPR (Localized Surface Plasmon Resonance) is generated on structured surfaces of nano discs of gold, that allow monitoring of biological interactions in real time and without the need of markers. The nanoplasmonic biosensor allows analysis of human samples in a few minutes, without requiring reagents or additional instrumentation.[...]