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U6. Biomaterial Processing and Nanostructuring Unit

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U6. Biomaterial Processing and Nanostructuring Unit




    • Scientific Coordinator: Dr. Nathaly Segovia nvsegovia@icmab.es
    • Entities: Instituto de Ciencia de Materiales de Barcelona ICMAB-CSIC
    • Address: Campus de UAB, 08193, Bellaterra, Barcelona, Spain
    • Phone: +34 935 801 853
    • Fax: +34 935 805 729
    • Web: ICMAB








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Located at the Instituto de Ciencia de Materiales de Barcelona (ICMAB-CSIC), in Barcelona, and under the coordination of Professor Jaume Veciana and Prof. Nora Ventosa, current directors of NANOMOL Group, which is a research group with wide expertise and recognized excellence in the synthesis, processing and study of molecular and polymeric materials with chemical, electronic, magnetic and biomedical properties.  It gathers several laboratories, perfectly equipped, to perform the mission of this facility: the development, characterization, and large-scale production of molecular biomaterials of therapeutic or biomedical interest, with controlled micro-, nano- and supramolecular structure. One example of Key-Enabling-Technology (KET) available in this unit is a simple one-step methodology, DELOS-SUSP, based on the use of compressed fluids (CF), such as CO2, to prepare particulate materials with precise and reproducible structural characteristics at micro-, nano- and supramolecular levels (size, shape, internal structural gradients, supra­molecular organization and crystalline purity). This example shows one of the singularities of this unit is that counts with CF–based plants at different scales, from mL to L, which allow process development by QbD and process scale-up.


U6. Services & Rates

Active projects

TitleFundin: OrganismCall: Funding source Role
GA: 720942SMART FUNCTIONAL GLA-NANOFORMULATION FOR FABRY DISEASE – Smart-4-FabryUnión Europea (Comisión Europea)H2020-NMBP-2016-2017Coordinator
SAF2017-90810-REDIStrategic Promotion and coordinated management of Nanbiosis: Pronanbiosis IIAgencia Estatal de Investigación (AEI)Acciones de dinamización «REDES DE EXCELENCIA» -ICTS 2017Coordinator

Other projects

RefTitleFunding OrganismUnit Role
PI15/00272Design of intelligent nanoconjugates for the treatment of metastatic colorectal cancer.Instituto de Salud Carlos IIIParticipant
H2020-MSCA-ITN-2014-642196Integrated self-assembled SWITCHable systems and materials: towards responsive organic electronics - a multi-site innovative training action i-SwitchUnión Europea H2020Participant
2014 SGR 17Consolidation Research Group: Molecular Nanociènciai Materials Orgànics (NANOMOL)Generalitat de CatalunyaParticipant
CTQ2013-40480-RMolecular Bio- and Electro-active materials for the improvement of health and social well-being (Be-Well)MICINNParticipant
FP7-PEOPLE-2013-ITN nº 607721Nanochemistry of molecular materials for 2-photon functional applications. Nano2FunUnión EuropeaParticipant
MAT2013-50036-EXPCell Surface Vessel Engineering Using Dynamic Molecular Bioinfecting (DYNAMO)MINECOParticipant
RTC-2016-4567-1Nanocapsules containing active ingredients for the topical treatment of dermatological diseases (NANO4DERM)MINECOParticipant
RTC-2014-2183-SApplication of Quatsomes technology for the development of a new range of perfumed softeners with lower environmental impactMINECOParticipant
201260E080Self-assembly, Nanostructuring and Processing of Functional Organic Molecules and their ApplicationsMinisterio de Ciencia e InnovaciónParticipant
MAT2016-80826-RMolecular materials and supramolecular organizations for therapy, diagnosis and tissue engineering (MOTHER)MINECOParticipant
RTC-2014-2207-1TERARMET: Development of therapies for the treatment of rare congenital metabolic diseasesMINECOParticipant




  • Munoz-Gomez J.L., Monteagudo E., Lloveras V., Parella T., Veciana J., Vidal-Gancedo J.. Optimized polarization build-up times in dissolution DNP-NMR using a benzyl amino derivative of BDPA. RSC Advances. 2016;6(32):27077-27082.
  • Cordoba A., Hierro-Oliva M., Pacha-Olivenza M.A., Fernandez-Calderon M.C., Perello J., Isern B. et al. Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti-O-P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion. ACS Applied Materials and Interfaces. 2016;8(18):11326-11335.
  • Cabrera I., Abasolo I., Corchero J.L., Elizondo E., Gil P.R., Moreno E. et al. α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration. Advanced Healthcare Materials. 2016;5(7):829-840.
  • Cano-Garrido O., Sanchez-Chardi A., Pares S., Giro I., Tatkiewicz W.I., Ferrer-Miralles N. et al. Functional protein-based nanomaterial produced in microorganisms recognized as safe: A new platform for biotechnology. Acta Biomaterialia. 2016;43:230-239.

News U6

09 Apr

Infertility: Exosomal microRNAs in seminal plasma as sensitive and specific biomarkers of the presence of testicular spermatozoa for azoospermia

NANBIOSIS ICTS coordination equipment has recently received from researchers of Human Molecular Genetics Group of Bellvitge Biomedical Research Institute (IDIBELL) a publication mentioning NANBIOSIS in the Acknowledgements for its participation in the results of its investigations. The article has been publish by the journal Human Reproduction of OXFORD UNIV PRESS  with Quartile 1/ Decile 1. The study carried out by  Maria Barcelo, Ana Mata, Lluís Bassas, and Sara Larriba demonstrates the potential of several miRNAs contained in small extracellular vesicles (sEVs) of seminal fluid as sensitive and specific biomarkers for selecting those azoospermic individuals with real chances of obtaining spermatozoa[...]

06 Apr

NANOMOL group, coordinator of NANBIOSIS Unit 6 collaborates with the VHIR in the developement of a new nanomedicine for the treatment of a childhood cancer

Within the MOTHER project (Molecule-based materials and supramolecular organizations for therapy, diagnosis and tissue engineering), the NANOMOL group from ICMAB collaborates with the Vall d’Hebron Institute of Research (VHIR), on the developement of a new nanomedicine for the treatment of high risk neuroblastoma, one of the most typical childhood cancers. Now, researchers from VHIR have identified new microRNAs that reduce the progression of this type of cancer. The participation of NANOMOL group and NANBIOSIS unit 6 Biomaterial Processing and Nanostructuring Unit, as experts in nanoparticles and nanovesciles for nanomedicine, is on the synthesis of the adequate nanocapsules to protect, stabilize and direct this microRNAs molecules to t[...]

11 Feb

NANBIOSIS Scientific Women in the International Day of Women and Girls in Science

Today February 11 is the International Day of Women and Girls in Science, a day to raise awareness of the gender gap in science and technology. According to the United Nations, while yet women and girls continue to be excluded from participating fully in science, science and gender equality are vital to achieve the internationally agreed development goals, including the 2030 Agenda for Sustainable Development. Thus, in recent years, the international community has made a great effort to inspire and promote the participation of women and girls in science. NANBIOSIS wants to acknowledge  the efforts made by scientific women who struggle every day to contribut[...]

04 Feb

NANBIOSIS Against Cancer

The World Health Organization, the International Cancer Research Center (IARC) and the International Union Against Cancer (UICC) celebrate February 4 of each year as World Cancer Day Every year, 14 million new cases of cancer are diagnosed worldwide and the disease causes 8.2 million deaths. Thanks to scientific research, great advances have been made in the fight against cancer. Through surgery, chemotherapy or radio therapy and, in the last 20 years, through immunotherapy, hormonal treatment or cell therapies, tools have been obtained to improve early diagnosis and treatments, increasing cancer survival by 20%. The only way to understand cancer and,[...]

01 Feb

Quatsomes. A new family of nanocarriers for drug delivery

The XXXVII edition of the Biennial Meeting of the Spanish Royal Society of Chemistry (RSEQ) will be held from the 26th to the 30th of May in Donostia-San Sebastian.  Prof. Jaume Veciana, Scientific Director of NANBIOSIS and unit 06  of NANBIOSIS -ICTS  Biomaterial Processing and Nanostructuring Unit, will present on May 28th 2019 a lecture entitled “Quatsomes. A new family of nanocarriers for drug delivery” at the Simposium “From Chemistry to Nanomedicine” (http://bienal2019.com/simposios.php). In this lecture the advantages and disavatages of such a kind of nanocarriers will be presentaed as well as some of their applications as nanomedicines.” Deadline for sending abstracts: January 30 (http://bienal2019.com/en/communications.php)&nbs[...]

22 Nov

Lysosomal Rare Disorders: Focus on Fabry Disease

Last November 19, Vall d’Hebron held a seminar  on Lysosomal Rare Disorders: Focus on Fabry Disease as  part of the Rare Diseases Program at the Vall d’Hebron Campus, in collaboration with the European Commission, the Center for Biomedical Research Network on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) and the CIBBIM-Nanomedicine at Vall d Hebron Research Institute (VHIR) through the Smart-4-Fabry projec In the  second plenary session, moderated by Nora Ventosa and Simó Schwartz, Scientific Directors of NANBIOSIS units 6 and 20 and devoted to New therapeutic strategies for lysosomal disorders, the speakers presented their findings regarding biomarkers, genetic variants and treatment protocols.[...]

31 Oct

FUNCATH: Prevention of infectious diseases with functionalized catheters awarded by La Marató de TV3

FUNCATH project,  coordinated by scientists of NANOMOL  group, led by Dr. Imma Ratera, has been awarded by Fundació La Marató de TV3 . NANOMOL is the research group that coordinates NANBIOSIS U6 Biomaterial Processing and Nanostructuring Unit, from ICMAB-CSIC and CIBER-BBN. Fundació La Marató de TV3 2017 call was dedicated to infectious diseases and awarded 36 projects among the 186 evaluated according to their excellence, methodology and relevance. FUNCATH is the project for Prevention of infections related to vascular catheters by functionalizing catheters impregnated with thermically activatable hydrogels with broad spectrum antimicrobial agents, whose ultimate goal is the development of vascular catheters coated with multibiofunctiona[...]

11 Oct

Nanoparticles characterization techniques of NANBIOSIS unit 6

The Unit 6 of NANBIOSIS, Biomaterial Processing and Nanostructuring Unit, has organized during the days 8 to 11 of October in the ICMAB-CSIC a course of characterization of Nanoparticles showing some of their techniques to the CSIC researchers. Amable Bernabé, the technician of unit 6 of NANBIOSIS has shown the theory and practice of some methods to characterize nanoparticles and how to handle the necessary equipment. Specifically, these techniques were: Dynamic Light Scattering (DLS) with Zetasizer Nano ZS (Malvern Instruments) Size distribution Z Potential Nanoparticle Tracking Analysis (NTA) with Nanosight NS300 (Malvern Instruments) Size distribution Particle concentration Fluorescence Light Scattering (LS) with Mastersizer 2000 (Malvern[...]

U6-Biomaterial Processing and Nanostructuring Unit
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