U6. Biomaterial Processing and Nanostructuring Unit
- Scientific Coordinator: Dr. Nathaly Segovia firstname.lastname@example.org
- Entities: Instituto de Ciencia de Materiales de Barcelona ICMAB-CSIC
- Address: Campus de UAB, 08193, Bellaterra, Barcelona, Spain
- Phone: +34 935 801 853
- Fax: +34 935 805 729
- Web: ICMAB
- U6-S01. Use of High-pressure laboratory-scale plant with 50, 100 and 300 m reactors for the processing of biomaterials. Processing of cytotoxic compounds when required. (Remote) OUTSTANDING
- U6-S02. High-pressure phase analysis – solubility, emulsification (Remote) OUTSTANDING
- U6-S03. Thermal analysis of solid materials(Remote) OUTSTANDING
- U6-S04. Analysis of particle size, concentration and Z-potential of nanoparticles (On-site&Remote) OUTSTANDING
- U6-S05. Analysis of particle morphology (Remote) OUTSTANDING
- U6-S06. Fluorescence spectroscopic analysis (On-site&Remote)
- U6-S07. UV-Vis spectroscopic analysis (On-site&Remote)
- U6-S08. Visual observation (On-site&Remote)
- U6-S09. Centrifugation (On-site)
- U6-S10. Treatment of sample by ultrasound probe (On-site)
- U6-S11. Specific density of powders (On-site&Remote) OUTSTANDING
- U6-S12. Packed (tapped) density(On-site) OUTSTANDING
- U6-S13. Detection of labeled nanoparticles and exosomes by fluorescence mode (On-site&Remote) OUTSTANDING
- U6-S14. Quantitative studies of biomolecular interactions by calorimetric measurements (On-site) OUTSTANDING
FOR THOSE SERVICES IDENTIFIED AS OUTSTANDING, AT LEAST 20% OF THEIR CAPACITY IS OPEN UNDER COMPETITIVE ACCESS. SEE ANNEX 1 OF ACCESS PROTOCOL FOR DETAILS ON % OF OPENNESS FOR EACH SERVICE
- U6-E01. High-pressure laboratory-scale plant with 50, 100 and 300 ml reactors for the processing of biomaterials.
- U6-E02. High-pressure phase analyzer for studying the thermodynamic behaviour of materials.
- U6-E03. Malvern Zetasizer Nano ZS particle size analyzer.
- U6-E04. Nanosight LM -20 for Nanoparticle Tracking Analysis.
- U6-E05. Nanosight NS-300 for Nanoparticle Tracking Analysis by fluorescence mode.
- U6-E06. Perkin-Elmer DSC 8500 differential scanning calorimeter.
- U6-E07. Olympus BX51 optical microscope with heating plate and fluorescence accessories.
- U6-E08. Perkin-Elmer LS 45 fluorescence spectrometer.
- U6-E09. Varian Cary 5 UV -Vis spectrometer.
- U6-E10. Quantachrome Ultrapyc 1200e helium pycnometer.
- U6-E11. Ultrasound probe and Autotap instrument for packed density measurements of powders.
- U6-E12. Malvern Morphologi G3 for advanced particle morphologi characterization.
- U6-E13. Microcalorimeter for measurements of biomolecular binding properties under Isothermal Titration Calorimetry (ITC)
- U6-E14. Four Glove Dispensing isolator for expermiments with highly active and cytotoxic compounds
- Munoz-Gomez J.L., Monteagudo E., Lloveras V., Parella T., Veciana J., Vidal-Gancedo J.. Optimized polarization build-up times in dissolution DNP-NMR using a benzyl amino derivative of BDPA. RSC Advances. 2016;6(32):27077-27082.
- Cordoba A., Hierro-Oliva M., Pacha-Olivenza M.A., Fernandez-Calderon M.C., Perello J., Isern B. et al. Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti-O-P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion. ACS Applied Materials and Interfaces. 2016;8(18):11326-11335.
- Cabrera I., Abasolo I., Corchero J.L., Elizondo E., Gil P.R., Moreno E. et al. α-Galactosidase-A Loaded-Nanoliposomes with Enhanced Enzymatic Activity and Intracellular Penetration. Advanced Healthcare Materials. 2016;5(7):829-840.
- Cano-Garrido O., Sanchez-Chardi A., Pares S., Giro I., Tatkiewicz W.I., Ferrer-Miralles N. et al. Functional protein-based nanomaterial produced in microorganisms recognized as safe: A new platform for biotechnology. Acta Biomaterialia. 2016;43:230-239.
Prof. Jaume Veciana, Scientific Director of NANBIOSIS: Olivier Kahn Plenary Lecture speaker at the ICMM 2018
Prof. Jaume Veciana, Scientific Director of NANBIOSIS has been honored with the Olivier Kahn Plenary Lecture given at the 16th International Conference on Molecule-Based Magnets (ICMM 2018), held on September 1-5, 2018, in Rio de Janeiro, Brazil. For further information: click her[...]
Nathaly Segovia, Scientific coordinator of NANBIOSIS U 6, Biomaterial Processing and naostructuring unit, explains in this video what the objective of her unit , the services they offer and their technologies in the field of drug delivery.[...]
Jaume Veciana and Imma Ratera (NANBIOSIS U6 Biomaterial Processing and Nanostructuring Unit) have supervised Manuel Souto’s PhD thesis entitled “Multifunctional Materials based on TTF-PTM dyads: towards new Molecular Switches, Conductors and Rectifiers”. The School for Doctoral Studies, together with UAB Alumni, organises an event every semester for the award of PhD degrees and PhD special prizes. With 66 PhD programmes, the UAB is one of the leading Catalan universities in the production of theses and generates approximately a third of the doctoral theses that are defended in the Catalan university system each year. The PhD special prizes confer value to theses which have received the qualification of excellenc[...]
Scientists of NANBIOSIS U6. Biomaterial Processing and Nanostructuring Unit, have recently pubished an article in the ACS Omega about the design 0f 3D platforms specific for T cell culture to improve the current T cell expansion systems to introduce new in vitro models and facilitate the broad use of ACT in the clinics. Adoptive cell therapy, i.e., the extraction, manipulation, and administration of ex vivo generated autologous T cells to patients, is an emerging alternative to regular procedures in cancer treatment. Nevertheless, these personalized treatments require laborious and expensive laboratory procedures that should be alleviated to enable their incorporation into the clinics. With the objectiv[...]
Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels–Alder Type Additions
NANBIOSIS Unit 6 Biomaterial Processing and Nanostructuring and Unit 3 Synthesis of Peptides collaborate in a research whose results are published by The Journal of Physical Chemistry B Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels–Alder Type Additions Adriana R. Kyvik, Carlos Luque-Corredera, Daniel Pulido, Miriam Royo, Jaume Veciana, Judith Guasch, and Imma Ratera The Journal of Physical Chemistry B 2018 122 (16), 4481-4490 DOI: 10.1021/acs.jpcb.8b01652 Stimuli-responsive self-assembled monolayers (SAMs) are used to confer switchable physical, chemical, or biological properties to surfaces through the application of external stimuli. To obtain spatially and temporally tunable surfaces, we present microcontact printed SAMs of a hydroquinone molecule that are used[...]
Judith Guasch, (NANBIOSIS Unit 6) has been granted with a Ramon y Cajal grant from the Spanish Goverment
Judith Guasch holds a senior postdoctoral research position at the NANOMOL group CIBER-BBN at ICMAB-CSIC that coordinates NANBIOSIS Unit 6 Biomaterial Processing and Nanostructuring Unit, after being awarded with a TecnioSpring fellowship (Marie Curie Fellow, Cofund – Catalan Government and EU). Since 2017 she is also head of a Max Planck Partner Group (Dynamic Biomimetics for Cancer Immunotherapy) in collaboration with the Max Planck Institute for Medical Research (Heidelberg, Germany). Judith’s research interests are focused on the design, synthesis, and fabrication of multifunctional molecular and supramolecular materials for biomedical applications. Special interest is devoted to study the cell-material interaction for improving novel adoptive cell therapies for the treatment of cancer.[...]
Yesterday took place in Barcelona, at Barcelona School of Management, Universitat Pompeu Fabra, a meeting of resarch groups and units of NANBIOSIS and CIBER-BBN and companies in the third B2B Forum organized by NANBIOSIS, in this case together with NANOMED SPAIN. Thirteen companies and twelve groups from CIBER-BBN and CCMIJU (ten of them coordinating NANBIOSIS units) got together to explain, through short presentations of ten minutes, those lines of their work aimed at finding synergies and potential collaborations in the area of Nanomedicine apllications in drug delivery and targeting. There was also a talk by a representative of CDTI (Spanis[...]
The equipment of NANBIOSIS U6-Processing of biomaterials and nanoestructuring, that at present are in several laboratories of the ICMAB-CSIC, are going to be transferred to their definitive location in the new laboratory of this NANBIOSIS unit. Given the large amount of equipment the process is expected to last two years, and itwill be done sequentially to continue to provide service to laboratory users. In this process, an engineer has been hired to play a key role, since he will not only be in charge of the transfer, but also to ensure the correct installation of equipment after its transfer and[...]