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Posts Taged arrhythmias

Equations that can save thousands of lives

Esther Pueyo, from the research group BSICoS, coordinator of Unit 27 of NANBIOSIS, explains for the program “En route with science” of Aragon Television, her research on arrhythmias: irregularities in the functioning of the heart. Arrhythmias are the cause of 25,000 deaths per year and half of hospital admissions in Spain.

First of all they study experimentally (extracting tissues from the heart of animals and humans) how the electrical activity of the said tissues is. Then, the information collected is introduced in mathematical models to understand the heart and to make predictions of what can happen in the future and why some behaviours in the heartbeat of a patient can be dangerous. For that process, stochastic equations are used that do not have a single solution and adapt to the variability of biology. These equations allow researchers to better interpret what the electrocardiogram signals say and to make predictions of risk with greater reliability. This is a multidisciplinary research in which mathematicians, engineers, physicists, biologists, electrophysiologists collaborate to make the most of the data obtained from patients.

To carry out this research, Esther Pueyo heads the European project “MODELAGE” for which she obtained a “Starting Gran” with funding of 1.5 million euros. They model patient data collected for the project to obtain different models, not only for each individual, but also for the different tissues or cells of the same patient.

In this project they study the aging of the heart, but in the BSICoS group, they also study other types of arrhythmias, such as heart attack, ischemia, or heart behaviour of astronauts participating in a special mission, who are at increased risk for arrhythmias or babies with congenital diseases that provide them with an increased risk of having arrhythmias.

Computational modelling necessary to reproduce the experimental and clinical observations and the signal analysis are be developed using the computing platform, Unit 27 of NANBIOSIS.

For further information:

http://alacarta.aragontelevision.es/programas/en-ruta-con-la-ciencia/  Cap 44

Equations that can save thousands of lives
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Esther Pueyo nominated for the awards Aragonese of the Year 2015 for her research on aging heart, carried through the computational capabilities of Unit 27 of NANBIOSIS  

Esther Pueyo, researcher at the group of CIBER-BBN, BSICoS, which coordinates Unit 27 of NANBIOSIS, has been nominated for awards Aragonese of the Year  in the category of science and research. Esther develops a project considered of reference by European Union that studies aging heart through mathematical and computational tools combined with experimental and clinical work aimed at proposing new markers of risk for arrhythmias.

The Newspaper El Periódico de Aragon calls for the twenty second consecutive year Aragonese of the Year, a competition that recognizes the personal and professional Aragonese citizens and groups who develop their work in different fields, always with social significance merits.

The Aragonese of the Year contest is divided into five categories, with four nominations each. One that gets the most votes will rise to the Aragonese Year award in the cathegories: Company, Sports, Human Values, Science and Research and Culture

Esther Pueyo (U27 Nanbiosis) nominated for Aragonese of the Year 2015 for her research on aging heart
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Government of Aragón, Spain, paid tribute to the seven scientists who have a grant of European excellence and develop their projects at the University of Zaragoza: Jesús Santamaría, Diego Gutierrez, Igor Irastorza, Esther Pueyo, Manuel Arruebo, José Manuel García Aznar and Jesús Martínez de la Fuente.

President of the Government of Aragon, Javier Lambán, has personally expressed his gratitude and appreciation for the work of seven researchers from the University of Zaragoza who have been granted with projects of excellence funded by the European Research Council.

Jesús Santamaría, Scientific Director of Unit 9 of NANBIOSIS, with an Advanced Grant funded with 1.85 million euro, is working on a project to develop a microreactor that enables the industry to save energy and raw materials.

Esther Pueyo, member of the research group BSICoS of CIBER-BBN, which coordinates Unit 27 of NANBIOSIS, has a Starting Grant of 1.5 million and is studying the aging of the heart to propose new markers of risk for arrhythmias in the aging population.

Manuel Arruebo member of the research group Nanostructured films and particles of CIBER-BBN, which coordinates Unit 9 of NANBIOSIS, with a Grant Consolidator 1.5 million for the project Nanohedonism, develops injectable nanoparticles created with microfluidic reactors for the controlled and remote delivery of drugs in the treatment of chronic pain.


Nanbiosis_U27_U9_Three researchers of NANBIOSIS among the seven Aragonese scientists granted with an ERC.
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