Preclinical Study for Brain Tumor with Novel Contrast Agents for MRI
Ana Paula Candiota and Carles Arús, Scientific Cordinator and Scientific Director of U25 of NANBIOSIS, NMR: Biomedical Applications I have participated in the research published by ACS Applied Materials & Interfaces Journal that include a preclinical study carried for brain Tumor.
Extensive attention has been paid on designing and developing functional imaging contrast agents for providing accurate noninvasive evaluation of pathology in vivo. However, alse-positives or ambiguous imaging and the lack of a robust strategy for simultaneous dual-mode imaging remain to be fully addressed. One effective strategy for improving it is to design magnetic resonance imaging (MRI) contrast agents (CAs) with intrinsic T1/ T2 dual-mode imaging features. In this joint work from ICN2 and CIBER-BBN members, the development and characterization of nanostructured coordination polymers (NCPs) which exhibit dual mode T1/ T2 MRI contrast behavior is described.
The MR characterization was performed at U25 of NANBIOSIS
Article of reference:
“Dual T1/T2 Nanoscale Coordination Polymers as Novel Contrast Agents for MRI: A Preclinical Study for Brain Tumor“. S. Suárez-García, N. Arias-Ramos, C. Frias, A. P. Candiota, C. Arús, J. Lorenzo, D. Ruiz-Molina, and F. Novio ACS Applied Materials & Interfaces Article ASAP
