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Posts Taged pluronic-f12

A new polymeric nomedicin facilitates simultaneous pharmacological and gene silencing therapies

Simó Shwartz, Scientific Director of NANBIOSIS U20 In vivo Experimental Platform, has recently published an interesting article “Efficient EFGR mediated siRNA delivery to breast cancer cells by Cetuximab functionalized Pluronic® F127/Gelatin” issued by  Chemical Engineering Journal. The research group of Dr Schwartz has managed to create a micelle formed by a combination of polymers and gelatin that allows to transport effectively large quantities of both nucleic acids and drugs inside. The system also leads to the periphery a series of carboxylic groups that allow anchoring in a very easy way any type of directing molecule such as for example a peptide or antibody. 

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