Use of High-pressure laboratory-scale plant
with 50, 100 and 300 m reactors for the processing of biomaterials. Processing of cytotoxic compounds when required.
Preparation of soft molecular materials with controlled structure at supramolecular, micro- and nanoscopic level, using one-step methodologies based on green compressed fluids (i.e. compressed and supercritical CO2).Micro- and nanoparticulate single compounds with high supramolecular homogeneity (i.e., pure polymorphic phases, materials with single polymer folding, etc.).
- Particulate polymeric matrix uniformly loaded with active compounds (therapeutics, cosmetic ingredients, catalyst, pigments, and dyes, etc.)
- Dispersed systems (suspensions, liposomes, emulsions, vesicles) with narrow particle size distribution and high morphological homogeneity.
- Porous materials, either crystalline or amorphous, with defined porosity and porous size.
Customer benefits
Lab-scale high pressure systems, based on a 50 mL, a 100 mL and a 300 mL stirred high pressure autoclaves equipped with pumps for the supply of compressed fluids and liquid solutions. The high-pressure systems can also optionally be equipped with several filters, manometers, thermocouples, and back pressure regulators. The maximum operative pressure is 23 MPa and the maximum operative temperature is 200 °C.
The 300 mL system is also equipped with a mass flowmeter, and a data acquisition system.
All the plants have been designed for micro- and nanostructuring molecular and soft materials.
Target customer
- Pharmaceutical industry
- Food Industry
- Chemical industry
- Materials research centers
References
- M.Köber, et al., J.C.I.S 2023, 631, 202-211.
- E.Elizondo,et al., J. Am. Chem.Soc. 2012, 134, 1918−192.
- I.Cabrera, et al. Nano Lett. 2013, 13, 3766−3774.