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Singular

Singular

U29-S02. Modification of oligonucleotides. (Remote) OUTSTANDING

Modification of oligonucleotides during and post synthesis to meet user requirements:

  • Conjugation of oligonucleotides with fluorophores (fluoresceine, Cy3, Ct5, etc..) and other types of small molecules such as biotine, lipids.
  • Conjugation to peptides.
  • Phosphorothioate linkages
  • Modified backbones such as locked nucleic acids (LNA), 2’-O-alkyl-RNA, etc..
  • Modified nucleobases: 2-aminopurine, 5-methyl-dC, etc…
  • 5’, 3’-modifications such as 5’-, 3’-amino, 5’-, 3’-thiol, etc..
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U29-S03. Special nucleotides for oligonucleotide synthesis. (Remote) OUTSTANDING

Special nucleotides for oligonucleotide synthesis

For those services identified as outstanding, at least 20% of their capacity is open under competitive access. See Annex 1 of ACCESS PROTOCOL (provided by Nanbiosis) for details on % of openness for each service

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U29-S01. Synthesis of oligonucleotides and characterization (On-site & Remote). OUTSTANDING

Synthesis of oligonucleotides at various different scales (100 mg to 5 mg) and purification using HPLC and/or desalting.

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U19-S02. Animal Model Studies (Onsite&Remote) OUTSTANDING

Preclinical regulatory in vivo toxicity, local and systemic tolerance and PK/PD studies; dosing of test and specimen drawing, biocompatibility studies of medical devices; Safety studies: Nervous, cardiovascular and respiratory systems.

Security testing of advanced therapies using small and large animals models.

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U10-S09. Characterization and development of pulmonar formulations (On-site&Remote) OUTSTANDING

Characterization and development of pulmonar formulations

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U10-S08. 3D bio-impression of scaffolding for regenerative medicine (On-site&Remote) OUTSTANDING

3D bio-impression of scaffolding for regenerative medicine

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U23-S09. Quality control for Human Assisted Reproduction clinics (On-site&Remote) OUTSTANDING

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U23-S08. Oosight system (On-site&Remote) OUTSTANDING

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U23-S07. Laser System and Biopsed of blastomeres (On-site&Remote) OUTSTANDING

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U23-S06. IMSI system (On-site&Remote) OUTSTANDING

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