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U26. NMR: Biomedical Applications II

Ciber bbn

U26. NMR: Biomedical Applications II

  • Scientific Director: Prof. Ramon Martinez Máñez  rmaez@qim.upv.es
  • Scientific Coordinator: Dr. Salvador Gil salvador.gil@uv.es
  • Entities: Universitat de Valencia (UV)
  • Address: C/Dr. Moliner, 50, Edificico Investigación, 1º Pl., 46100, Valencia, Spain
  • Phone: +34 963877343
  • Tel Prof. Martínez: +34 963877343 ; Tel Dr. Gil : +34 963543135
  • Web: UV
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Description

Located in the Faculty of Medicine of the University of Valencia (UV) has a laboratory with a NMR (14T) for acquiring unique metabolic profiles of biofluids, cell lines and tissues. This Unit is coordinated by Dr. Ramón Martínez Máñez, PI of the Applied Molecular Chemistry Group of the Universidad Politécnica de Valencia, together with Dr. Salvador Gil, Director of the Central Service for Experimental Research (SCSIE).

Active projects

TitleFundin: OrganismCall: Funding source Role
SAF2017-90810-REDIStrategic Promotion and coordinated management of Nanbiosis: Pronanbiosis IIAgencia Estatal de Investigación (AEI)Acciones de dinamización «REDES DE EXCELENCIA» -ICTS 2017Partner
PICCOLO-732111Multimodal highly-sensitive PhotonICs endoscope for improve in vivo COLOn Cancer diagnosis and clinical decision supportEuropean Commission-H2020H2020-ICT-2016-1Partner
0624_2IQBIONEURO_6_EPromotion of an R&I network in biological chemistry for the diagnosis and treatment of neurological diseasesEuropean Union Interreg : European Territorial Co-operationPOCTEP Interreg España-PortugalPartner

Other projects

RefTitleFunding OrganismUnit Role
MAT2015-64139-C4-1-RINTELLIGENT NANOMATERIALS, PROBES AND DEVICES FOR THE INTEGRATED DEVELOPMENT OF NEW TOOLS APPLIED TO THE BIOMEDICAL FIELDMINISTERIO DE ECONOMIA INDUSTRIA Y COMPETITIVIDADParticipant
MAT2015-64139-C4-C-RCHROMOGENIC AND FLUOROGENIC CHEMOSENSES FOR THE DETECTION OF NEUROTRANSMITTERSMINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDADParticipant
PROMETEOII/2014/047New approaches for the design of controlled release materials and the detection of dangerous compoundsGeneralitat ValencianaParticipant
AP2012-1478HELP CONV FPU 2012 - DE LA TORRE PAREDES, CRISTINAMinisterio de Educacion, cultura y deporteParticipant
MAT2012-38429-C04-01Development of functionalized materials with nanoscopic doors for controlled release applications and sensors for the detection of ammonium nitrate, sulfuric acid and COMinisterio de Economia y CompetitividadParticipant
UPV-FE-16-A1CONSTITUTION OF A SMART DRUG DISCOVERY PLATFORMParticipant
UPV-FE-15-A2Development of nanomaterials and sensors for early and non-invasive diagnosis and prognosisUNIVERSIDAD POLITECNICA DE VALENCIAParticipant
AP2013-06017HELP CONTRACT FPU 2013-SANCHEZ CABEZASMInisterio de Educacion, Cultura y DeporteParticipant

Publications

2016

  • Rosales A.M., Aznar E., Coll C., Garcia Mendoza R.A., Lorena Urbano Bojorge A., Gonzalez N.F. et al. Study of the dependency of the specific power absorption rate on several characteristics of the excitation magnetic signal when irradiating a SPION-containing ferrofluid. Journal of Magnetics. 2016;21(3):460-467.

News U26

26 Nov

The Nanomedicine Revolution

Yesterday, November, 25 took place, within the the program of the Ateneo of the EINA (School of Engineering and Architecture of Aragón), the online conference on “The Revolution of Nanomedicine” by Ramón Martínez Máñez. The Conference chair, Jesús Martínez de la Fuente, Principal Investigator of the BIONANOSURF group of CIBER-BBN and the Institute of Nanoscience and Materials of Aragón, introduced the guest, Ramón Martínez Máñez, Scientific Director of CIBER-BBN, highlighting “his creativity in the use of his systems and how he combines them with different diagnostic release systems, combining organic chemistry, surface chemistry, applications in biotechnology and giving way to[...]

13 Nov

How to delay vision loss in hereditary retinal dystrophies? Looking for the most effective and economical pharmacological nanotherapy

Researchers from the CIBER-BBN and NANBIOSIS are participating in a new project that aims to achieve the most effective, specific and economical pharmacological nanotherapy that allows delaying the death of retinal cells and subsequent loss of vision in hereditary retinal dystrophy. retinitis pigmentosa, regardless of the genetic defect causing the disease. In this project, coordinated by the researcher Regina Rodrigo, the ONCE and the Prince Felipe Research Center (CIPF) of Valencia collaborate, together with researchers from the CIBER of Rare Diseases (CIBERER) and the Manises Hospital in Valencia. On behalf of the CIBER-BBN, the scientific director, Ramón Martínez Máñez, together[...]

08 Oct

New test trials to diagnose Covid 19: Ramon Martinez, Scientific Director of CIBER-BBN is interviewed by Spanish Television

Ramón Martinez, Scientific Director of CIBER-BBN and NANBIOSIS unit 26 NMR: Biomedical Applications II is interviewed by Spanish Television about the research he is coordinating at the Polytechnic University of Valencia to develop new tests as an alternative to PCR. Dr. Elena Aznar CIBER researcher at IQMA-IDM-UPV group explains how work these test that allow to diagnose quickly, easily, reliably and cheaply if a person is or has been infected by the SARS-COV-2 virus. Ramón Martínez Máñez, leader of the project, reports on the point where the investigation is, as well as the difference of these tests with PCR or[...]

29 Sep

COVID-19 detection system: a fast, cheap and easy to use alternative to PCR.

PCR (acronym in English for “Polymeric Chain Reaction”), is a type of diagnostic test for the detection of infectious diseases. The PCR diagnosis of COVID-19 used since the outbreak of the pandemic offers a high level of specificity and sensitivity but presents a certain degree of complexity, requiring specialized personnel and is expensive. Researchers from Polytechnic University of Valencia (UPV), the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO), the La Fe Health Research Institute (IIS La Fe) and the consortium Centro de Investigación Biomédica en Red de Bioengineering, Biomateriales y Nanomedicina (CIBER-BBN) has[...]

22 Sep

II Conference on Nanotoxicity. “Dosis sola facit venenum”

NANBIOSIS has participated in the organization of the on-line Conference on Nanotoxicity in collaboration with, CIBER-BBN, Nanomed Spain and Materplat, to debate about the efect of nanotoxicity of nanoparticles and nanotechnologies in health. The session has been started by Ramon Martinez Mañez, Scientific Director of CIBER-BBN and NANBIOSIS U26 NMR: Biomedical Applications II. Isabel Rodriguez (GAIKER Technlogy Center) has taking about tools for risk management of nanomatials differentiating between tools and strategies and explaining their experience in studies carried out. Luis Rojo del Olmo investigador del Grupo de Biomateriales del Instituto de Ciencia y Tecnología de Polímeros del CSIC y del CIBER-BBN) has spoken[...]

12 Jun

Seminar on Molecular probes and gated materials in biomedical applications by Ramón Martínez, now in youtube

Last June 8, 2020,  Ramón Martínez Máñez, Scientific Director of CIBER-BBN and NANBIOSIS U26, gave an on line seminar, hosted by Jaume Veciana and Anna Roig will from ICMAB-CSIC on Molecular probes and gated materials in biomedical applications and communication between nanoparticles. If you missed the seminar, you can see it now on YouTube: More information at the ICMAB website.[...]

08 Jun

NANBIOSIS researchers featured in the 15th Edition of Spanish Researchers Ranking

The 15th edition of the Webometrics Ranking of World Universities has been published, ranking researchers in Spain as well as Spaniards doing research abroad. A total of 11 Directors of NANBIOSIS units appear on the most recent list, featured on the top 2000. The list is ordered by the h-index, a metric that calculates research impact based on a correlation of papers published and number of citations, and then by number of citations. The result is a list of whose’s publications have had more impact online. NANBIOSIS researchers featured are Fernando Albericio (#207), scientific director of U3 Synthesis of Peptides[...]

27 May

Peptide‐Capped Mesoporous Nanoparticles: Toward a more Efficient Internalization of Alendronate.

Osteoporosis is an illness which appears when the osteoblast/osteoclast activities are unbalanced taking place bone resorption (caused by osteoclasts) in higher extension than bone formation (induced by osteoblasts). Alendronate is one of the most used drugs for osteoporosis treatment despite its scarce bioavailability. In an attempt to improve it, gated mesoporous silica nanoparticles, for the controlled release of alendronate, have been synthesized and characterized. These hybrid nanoparticles include labelled alendronate inside the porous, those porous are capped with a peptide designed to be selectively cleaved by cathepsin K enzyme (overexpressed in osteoclasts). Two CIBER-BBN units of the ICTS NANBIOSIS wer[...]