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Nanbiosis

10 Jan

U29.-Oligonucleotide-Synthesis-Platform
DNA nanotechnologists are in mourning

At the end of the XXth century Nanotechnology appeared as one of the more powerful technologies for the future. At that time material sciences were able to produce nanomaterials with exquisite size control and atomic force, microscopy was able to visualize objects in the nanoscale and photolithography arrived to their physical limits in the preparation of computer chips threatening Moore’s law. This empirical law saying that as transistor components shrank, the number per chip doubled about every 18 months, was acting from 1971  (Intel’s first chip) to billions in the present times.  At these times, one crucial development was t[...]

21 Dec

The Medicine of the Future needs the Nanomedicine Revolution. This is why

The medicine of the future is an increasingly tackled topic. In the context of global concern for the sustainability of the health system (chronic diseases, new disorders, aging population and financing problems), nanomedicine could promote more affordable and personalized health care and improve the quality of life of the patients. Between innovative techniques already implemented and concepts that evoke science fiction (nanobots, fluorescent particles working as spies, tiny Trojan horses introduced into our body …), nanomedicine generates great expectations. Nanomedicine, what is it exactly? Nanomedicine is the application of nanotechnology to medicine, that is, the use of nanotechnologic systems for[...]

16 Sep

Microfluidic devices: The process of development

The development of microfluidic devices is very significant for in-vitro diagnostic devices, biomarkers and organ-on-a-chip applications. The techniques, the materials and the equipment used for the fabrication of these devices, are as important as the strategy followed to obtain them. And at the Nanotechnology unit of NANBIOSIS U7– (MicrofabSpace and Microscopy Characterization Facilities of IBEC), we own the tools, the know-how and the expertise to accomplish such a goal. We regularly guide the process of design, in collaboration with the final user, we customize the technology needed to get the product and complete the fabrication of the microfluidic device, drawing[...]

07 Feb

The Need to Determine the Therapeutic Window of Novel Targeted Anticancer Nanomedicines

The Nanotoxicology Unit of CIBER-BBN ICTS NANBIOSIS, leaded by Ramon Mangues at the Research Institute of the Hospital de Sant Pau is devoted to evaluate effectiveness and toxicity of novel nanoparticles.  This Unit advises clients on the need to study simultaneously anticancer activity and associated toxicity. Thus, preclinical evaluation of novel Nanomedicines is usually carried out performing studies that assess their therapeutic effect, separated from additional experiments devoted to evaluate the toxicity associated with treatment. The dosage used to assess the therapeutic effect, often, significantly differs from the one used to study toxicity, since one is aiming to know t[...]

18 Dec

Printed sensors, a low cost alternative for clinical detection

In today’s society there is a great interest in developing new technologies that allow low-cost mass manufacturing, also called “rapid prototyping” or “additive manufacturing”. Rapid prototyping includes technologies such as sterolithography, 3D printing, laser sintering or printed electronics, among others. All of these share digital design and manufacturing from the consecutive addition of layers, that is, techniques that allow creating almost any shape or geometric feature in a very fast time.Printed electronics consists of printing inks on different types of substrates such as textiles, plastics, papers or films to make them “smart”. This technique is presented as an alternative to[...]

26 Feb

Fabry disease & Smart4Fabry project

The Fabry disease (FD) is a lysosomal storage disorder (LSD) that currently lacks an effective treatment. Lysosomes are spherical vesicles, which contain hydrolytic enzymes found in nearly all animal cells. LSDs are caused by lysosomal dysfunctions, usually because of the deficiency of a single enzyme required for the metabolism of macromolecules such as lipids, glycoproteins and mucopolysaccharides. Fabry disease is a progressive, X-linked inherited disorder caused by deficiency or absence of the α-galactosidase A (GLA) activity, an enzyme involved in the glycosphingolipid metabolism. The substrates of GLA are glycosphingolipids, being the primary substrate the globotriaosylceramide (Gb3). Therefore, the failure of GLA activity leads[...]

04 Feb

NANBIOSIS Against Cancer

The World Health Organization, the International Cancer Research Center (IARC) and the International Union Against Cancer (UICC) celebrate February 4 of each year as World Cancer Day Every year, 14 million new cases of cancer are diagnosed worldwide and the disease causes 8.2 million deaths. Thanks to scientific research, great advances have been made in the fight against cancer. Through surgery, chemotherapy or radio therapy and, in the last 20 years, through immunotherapy, hormonal treatment or cell therapies, tools have been obtained to improve early diagnosis and treatments, increasing cancer survival by 20%. The only way to understand cancer and,[...]

14 Nov

Drive Pannel Diabetes - Nanbiosis
Diabetes mellitus and pancreatic islet transplant: DRIVE

Today in the World Diabetes Day it is a good moment to remember The Patient Panel of the European project DRIVE- Diabetes Reversing Implants, held in Vitoria (Alava) on June 2 where researches and doctors met with patients and families. The Panel was organized by the NanoBioCel group of CIBER BBN and NANBIOSIS Unit 10 Drug Formulation, with the purpose of letting know the DRIVE project to patients and concect patients with the project scientists and experts in pancreas and stem cell transplantation. Thus, one of the most important health objectives of the European Union was met: to promote direct[...]

19 Jul

Mechanical Characterization of soft biological tissues - Nanbiosis
Mechanical Characterization of soft biological tissues

The experimental study of the mechanical properties of biological tissues is of vital importance. Thorough research into themechanical response of biomaterials is the basis for the creation ofmodels which can accurately reproduce the mechanical behavior ofsuch materials. Adequate mechanical characterization of tissue materials is of paramount interest to the clinical simulations, diagnostic and tissue engineering fields – where the tissue structure, in contrast to classical mechanics application fields, is just simply a biological tissue. In order to obtain their material properties, classical engineering testing techniques have been applied to biologicalmaterials. To reproduce the mechanical behavior of these kinds ofmaterial, many[...]

16 Jan

U12-Nanostructured liquid characterization unit
Characterization of nanomedicines

The quick development of nanotechnology and its application in medicine have generated new alternatives for the diagnosis and treatment of diseases thanks to the novel methods of preparation, modification and characterization of nanomaterials. The knowledge about the behavior of matter at the atomic and molecular level has allowed the creation of tools and processes to observe manipulate and control biological structures on a scale between 100 and 10,000 times smaller than a mammalian cell. Nanomedicine is defined as the application of nanotechnology in view of making a medical diagnosis or treating or preventing diseases. It exploits the improved and often[...]

News about Nanbiosis

13 Jan

Best Emergeging Researcher Award in the Biomedical Area to Edorta Santos

Edorta Santos Vizcaíno has been awarded as Best Emerging Researcher in the biomedical area by the Bioaraba Health Research Institute in the XXII edition of the Research and Innovation Conference. This award aims to recognize the work of researchers under the age of 40 who carry out their research activity in any public center of the Araba Health Network (OSI ARABA UNIVERSITY HOSPITAL / BIOARABA). The main award´’s criteria are the quality of the research carried out, active participation in public and private research projects, fidelity to the line of biomedical research and the usefulness and interest of the researc[...]

12 Jan

New fluorescent nanovesicles for intracellular biomarker detection

A new work by researchers from the CIBER-BBN at the Barcelona Institute of Materials Science ICMAB-CSIC, together with a team from the University of Rome Tor Vergata, presents new nanovesicles capable of crossing biological barriers such as cell membranes, maintaining their sensory capacity, making them attractive probes for intracellular biomarker detection. “The development of probes capable of detecting the biological environment and signaling the presence of a specific target molecule is a challenge with relevance in a variety of biomedical applications, from drug administration to diagnostic tools” says Mariana Köber, one of those responsible of the investigation together with Nora[...]

11 Jan

The activity of Peptide T22 as antimicrobial drug opens new possibilities for the local control of bacterial infections related to tumors

Researchers of NANBIOSIS Units 1 and 18, from CIBER-BBN at the Institut de Biotecnologia i de Biomedicina (IBB-UAB) and the Institut de Recerca Sant Pau (IIB-Sant Pau) presents the finding of a significant antimicrobial activity in the targeting peptide T22, which is used for antitumor therapy directed against CXCR4 + stem cells, with clinical interest in more than 20 types of human cancer, including colorectal cancer. The study describes how said activity has a significant effect on several bacterial species of clinical importance: “we have detected antimicrobial activity associated with T22 and inhibition of biofilm formation on Escherichia coli, Staphylococcus[...]

28 Dec

New results evidence new biomarkers for early diagnosis of P. aeruginosa infections

Pseudomonas aeruginosa is a common multidrug-resistant pathogen that causes acute and chronic infections. However, P. aeruginosa, as many other bacterial species, has developed resistance to antibiotics being difficult to treat. For this reason diagnostic methods allowing detection at early  stages of the infection are required  and, therefore, efficient biomarkers of infection are very helpful. These fast diagnosis will help on the subsequent therapeutic treatment. The Nb4D group of CIBER-BBN and IQAC-CSIC (led by M.-Pilar Marco) has recently conducted a research to develop a highly sensitive, specific and reliable immunochemical assay to detect pyocyanin (PYO), one of the most important virulence factors[...]

24 Dec

Two great scientists and excellent people pioneers on Nucleic Acids Chemistry

Nucleic Acid Chemistry is an interdisciplinary discipline that combines organic chemistry, biochemistry, pharmacology, materials chemistry and biophysics. It started soon after the Watson–Crick model of DNA with the synthesis of the first dinucleotide, published in 1955. However, in the last decade, this field has blossomed, with the demonstration that Nucleic Acid Chemistry can provide innovative solutions to health problems such as vaccination, pathogen detection, and the treatment of metabolic or genetic diseases as well as providing important tools for the interrogation of cellular mechanisms. Profesor Ramon Eritja, Scientific director of the Oligonucleotides Synthesis Platform U29 from ICTS NANBIOSIS will chair[...]

22 Dec

1,800,000 euro for the improvement of NANBIOSIS laboratories

The final decision on the call for funding of Singular Scientific and Technical Infrastructures (ICTS) within the framework of the Recovery, Transformation and Resilience Plan in 2021 for has been published. These grants are intended to facilitate the execution of the Strategic Plans of the ICTSs included in the current National Map of ICTSs, through the execution of the investments provided for in their investment plans and declared of high priority by the Advisory Committee for Singular Infrastructures (CAIS). Two applications were submitted to this call by NANBIOSIS: one by the CIBER node named “Towards a new generation of Infrastructur[...]

21 Dec

The Medicine of the Future needs the Nanomedicine Revolution. This is why

The medicine of the future is an increasingly tackled topic. In the context of global concern for the sustainability of the health system (chronic diseases, new disorders, aging population and financing problems), nanomedicine could promote more affordable and personalized health care and improve the quality of life of the patients. Between innovative techniques already implemented and concepts that evoke science fiction (nanobots, fluorescent particles working as spies, tiny Trojan horses introduced into our body …), nanomedicine generates great expectations. Nanomedicine, what is it exactly? Nanomedicine is the application of nanotechnology to medicine, that is, the use of nanotechnologic systems for[...]

03 Dec

‘SAFE-N-MEDTECH’ and ‘PHOEHIX’ OITBs in CIBER-BBN and NANBIOSIS annual Conference.

National and international leading researchers met online last November 15 and 16 at the XV CIBER-BBN Annual Congress to discuss the latest advances in bioengineering, biomaterials and nanomedicine research, and promote further collaborations in the field. This year’s CIBER-BBN Annual Conference included three plenary lectures given by internationally recognized experts in the fields of SARS-CoV-2 infection and vaccination, biomedical signal processing for sleep disorders, and regenerative medicine and biosensors. In addition to a selection of internal collaborations, valorization projects and collaboration projects with the CIBER of Oncology, the three programs of the Precision Medicine Infrastructure (IMPaCT) were presented. NANBIOSIS ICTS[...]

01 Dec

Nanomedicine in the Medicine of the Future

Scientists of CIBER-BBN and NANBIOSIS ICTS have participated in the 4th Conference “Anticipating the Medicine of the Future”, which took place on November 30th, organized by the Roche Institute Foundation. The topics for this ediction had been identified by the Observatory of Trends in the Medicine of the Future: Pharmacogenomics, Nanomedicine and Epigenomic The event counted with three roundtables for discussion in relation to the three topics. The second one, on Nanomedicine, was moderated by Joaquín Arenas, Director of the Research Institute of the 12 de Octubre University Hospital. Ramón Martínez Máñez, Professor of Inorganic Chemistry at the Interuniversity Researc[...]

29 Nov

New therapeutic strategies for the treatment of advanced breast and colon cancer

Sara Montero, researcher of the “Drug Delivery and Targeting” of CIBER-BBN and VHIR, presented her thesis work on November 22 “Nanotecnnology mediated extrategies targeting cancer stem cells for advanced cancer tratment”, directed by Dr. Simó Schwrtz and Dr Diana Rafael. In vivo experiments where carried out through the Unit 20 of the ICTS NANBIOSIS. The work presented by Sara Montero shows two different types of therapeutic strategies for the treatment of advanced breast and colon cancer. Both strategies focus on blocking proteins essential for the survival and proliferation of cancer stem cells (CMC), known to be the main responsible for current therapeutic failures, tumor[...]

28 Nov

Extracellular vesicles secreted by cancer stem cells promote angiogenesis and disease progression

Patricia González, researcher of the “Drug Delivery and Targeting” of CIBER-BBN and VHIR, presented her thesis work on November 19 where she lays the foundations to understand the role of different subpopulations of extracellular vesicles (VEs) secreted by tumor models in the regulation of tumor plasticity, as well as its effect on the tumor microenvironment and disease progression. In the project, it has been described for the first time how the VEs secreted by the cancer stem cell subpopulation are responsible for activating fibroblasts in the tumor microenvironment and promoting angiogenesis, thus facilitating disease progression. Furthermore, it has been possib[...]

26 Nov

New Equipment available for the Regenerative Medicine Research Line of the U10 of NANBIOSIS

The Unit 10 of Drug Formulation of the ICTS NANBIOSIS coordinated by the CIBER-BBN NanoBioCel group directed by Jose Luis Pedraz, which belongs to the University of the Basque Country, has been present at the signing of the agreement that gives support by the Provincial Council of Alava within the framework of the Advance Pharma Development project, together with the research and technological development center TECNALIA.  With this agreement, the NanoBioCel research group will receive in the next two years (2021-2023) a contribution of 650,000 €, which will allow the hiring of research personnel and the purchase of specific equipment[...]

22 Nov

‘Point-of-care or PoC’ devices are able to directly detect the genetic material of the virus in just 30 minutes

Twenty five Spanish researchers linked to the Higher Center for Scientific Research, CSIC, who are working more directly on the project ‘Point-of-care tests for the rapid detection of SARS-CoV-2’ – Studies for the development of technologies effective diagnosis and early detection of SARS-CoV-2- have met since last Wednesday and until this Friday at the Benasque Science Center ‘Pedro Pascual’ to analyze the state or of the different programs and lines of research on the covid-19. After months of intense work, among the most outstanding achievements in relation to the detection of the genetic material of the virus, is the development[...]

15 Nov

Vaccines against Covid, biomedical signal processing for sleep disorders and regenerative medicine, at the XV CIBER-BBN Annual Conference

The CIBER for Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) will hold its XV Annual Congress, which will be held online for another year, on November 15 and 16. The conference will begin with a welcome that will be given by Cristóbal Belda, director of the ISCIII, and the scientific director of CIBER-BBN Ramón Martínez Máñez, and will aim to share advances in research in bioengineering, biomaterials and nanomedicine, in addition to advancing synergies with other disciplines and institutions. This year’s edition will include three plenary talks given by internationally recognized experts in the fields of SARS-CoV-2 infection and vaccination, biomedical signa[...]

04 Nov

Colloidal nanocrystals for energy applications

Semiconductors are materials used in a wide ranfe of applications since they are capable of capturing light and allowing us to take advantage of it. In addition, if we reduce its size to the nanometric scale we can activate additional very interesting properties On October 16, “Technoscience and Energy” took place in Inseec, Lyon (France), a science-industry transfer event between French and Spanish companies and researchers from the energy sector in France. Among the invited speakers was María Bernechea Navarro, ARAID Investigator, at the Institute of Nanoscience and Materials of Aragon at University of Zaragoza-INMA. In her talk, entitled “COLLOIDAL[...]

02 Nov

Nanobodies for biosening at the European Biosensor Symposium digital seminars

Next November 8, the researcher of NANBIOSIS U2 Custom Antibody Service (CAbS)  J.-Pablo Salvador will host the Seminar “Nanobodies for biosensing” in the framework of European Biosensor Symposium digital seminar series which are schedulled on the third Tuesday of every month. Nanobodies® (Nbs) are the recombinant binding domain from the heavy chain antibodies tipically produced from camèlids.  Besides their great potential as molecules in drug development, Nanobodies possess excellent functional properties that aid in their development for diagnostic tools. In this seminar, Dr. Salvador will explain the the outstanding properties of Nanobodies. Three graduate student speaker and up to five graduat[...]

29 Oct

Dr Ramón Mangues, new member of the Royal Academy of Pharmacy of Catalonia

Dr. Ramon Mangues, head of the Oncogenesis and Antitumor Group and Scientific Director of NANBIOSIS U18 Nanotoxicology Unit of CIBER-BBN at the Sant Pau Research Institute, has been recently elected as a new member of the Royal Academy of Pharmacy of Catalonia. The celebration will take place on November 8 at 7 pm, at the headquarters of the RAFC, (Royal Academy of Pharmacy of Catalonia) which was the headquarters of the old Hospital de la Santa Cruz since the 15th century, located at Calle del Hospital, 56, in Barcelona. During the event, Dr. Mangues will read his admission speech “Selectiv[...]

25 Oct

NANBIOSIS U6 opens its doors to students of Nanoscience and Nanotechnology Degree at UAB

NANBIOSIS U6, Biomaterial Processing and Nanostructuring Unit from CIBER-BBN and ICMAB-CSIC, has received today the visit of students of the 4th year degree in Nanoscience and Nanotechnology of the Auonomous University of Barcelona. During this visit, the students had the opportunity to get known of the facilities of Unit 6 of NANBIOSIS ICTS and the to work in a research laboratory. José Amable Bernabé has, Technical Coordinator of the unit, has shown the students the equipment for processing materials with compressed fluids and also some equipment for the characterization of particulate materials. In the Degree in Nanoscience and Nanotechnology at[...]

21 Oct

CIBER renews its ISO 9001: 2015 Quality Certificate for its Management System

CIBER | October 14, 2021 CIBER, the main partner of NANBIOSIS obtained, last month, the ISO 9001: 2015 accreditation, issued by the ENAC (National Accreditation Entity) through TÜV Rheinland Ibérica Inspection, Certification and Testing SA, by which the quality in the CIBER management system is certified. The scope of the quality management system defined in the certificate covers: “Staff and training management services, administrative accounting and communication management services for the Center for Biomedical Research on the Net”. CIBER keeps updated the Quality Management System (QMS) designed to continuously improve the effectiveness and efficiency of performance, through the consideration of t[...]

18 Oct

ISO 9001-2015 Quallity Management Certification for NANBIOSIS U12

NANBIOSIS U12 “Nanostructured liquid characterization unit” of IQAC-CSIC and CIBER-BBN, led by Dr. Carlos Rodriguez Abreu and D. Jordi Esquena, has implemented a Quality Management System for the scope of Technological service for characterization of colloidal dispersions, which fulfills the requirements of the standard ISO 9001:2015. An IQNet recognized certificate has been issued by AENOR last week. This certification will expand and consolidate the service  that Unit 12 of NANBIOSIS is giving to companies and public sector researchers and facilitate their integration in cooperative international projects. The ISO 9001 Standard is the most widespread Quality Management tool worldwide, with over[...]

15 Oct

Pablo Laguna talking about Physiologically driven biomedical signal processing at the Autonomous University of San Luis Potosí

Zaragoza, October 14th, 2021 Bsicos.i3a.es Pablo Laguna, Scientific Director of NANBIOSIS U27 High Performance Computing and researcher of BSICoS Group of I3A-UNIZAR and CIBER-BBN gave a talk about Physiologically driven biomedical signal processing at the Faculty of Physics at the Autonomous University of San Luis Potosí (UASLP) in Mexico. He explaned how biomedical signals convey information about biological systems and can emanate from sources of as varied origins as electrical, mechanical or chemical. In particular, biomedical signals can provide relevant information on the function of the human body. This information, however, may not be apparent in the signal due to measurement noise,[...]

14 Oct

Results of the POSITION-II Project “A pilot line for the next generation of smart catheters and implants”

Cáceres, October 14th, 2021 POSITION II has received funding within the Electronic Components and Systems for European Leadership Joint Undertaking (ECSEL JU) in collaboration with the European Union’s H2020 Framework Programme (H2020/2014-2020) and National Authorities, under grant agreement Ecsel-783132-Position-II-2017-IA. It promotes innovation in smart medical instruments and focuses in the next generation of smart catheters and implants by the introduction of open technology platforms for: miniaturization, in-tip AD conversion, wireless communication, MEMS transducer technology and encapsulation. These platforms are open to multiple users and for multiple applications. POSITION II will enable the further development of the European R&D and manufacturing[...]

08 Oct

“Ring Around the Rosy”

C2C12 myoblast cells differentiating into myotubes and adopting unusual shapes have been obtained and captured by resarchers of UAH and NANBIOSIS Unit 17 Confocal Microscopy Service (of CIBER-BBN and UAH) and and chosen photo of the month by the Spanish Society of Biochemistry and Molecular Biology (SEBBM) The picture illustrates the month of October on the calendar that the SEBBM publishes and distributes annually among all partners, and is part of the gallery of images that illustrate the activities of the SEBBM. Likewise, the photography will participate in the “Best Scientific Image of the Year” contest. The winning image is[...]

06 Oct

Piezoelectric-assisted micromanipulator for assisted reproduction research

Cáceres, 6/10/2021 Today the provider of a Piezoelectric-assisted micromanipulator installs this device in the CCMIJU’s Assisted Reproduction Lab and provides of specific training for its use. The acquisition of the micromanipulator is part of the project “Embryonic Genetics in Assisted Reproduction” (GENERA), co-funded by the European Regional Development Fund (ERDF) within the framework of Spain’s Plurirregional Operational Program for Singular Scientific and Technical Infrastructures (ICTS) 2014 -2020 and by Consejería de Economía, Ciencia y Agenda Cultural of  Junta de Extremadura. The objective of GENERA includes the purchase of three devices to expand services in the field of embryonic genetics as[...]

04 Oct

Intracoronary Delivery of Porcine Cardiac Progenitor Cells Overexpressing IGF-1 and HGF in a Pig Model of Sub-Acute Myocardial Infarction

Researchers of NANBIOSIS units U14 Cell Therapy unit, U21 Experimental operating rooms and U24Medical Imaging at JUMISC are coauthors of an article recently published by the journal Cells “Intracoronary Delivery of Porcine Cardiac Progenitor Cells Overexpressing IGF-1 and HGF in a Pig Model of Sub-Acute Myocardial Infarction“· Large animal studies have been carried out by the ICTS ‘NANBIOSIS’, specifically Units 14, 21, 22, and 24 of the JUMISC Human cardiac progenitor cells (hCPC) are considered a good candidate in cell therapy for ischemic heart disease, demonstrating capacity to improve functional recovery after myocardial infarction (MI), both in small and larg[...]

30 Sep

Scientific Communication course

We want to invite you to a practical and short course of Introduction to Scientific Communication organized by CIBER-BBN and NanoBioCellGroup – NANBIOSIS U10 Drug Formulation Unit. The course will take place on the 5th (two hours from 9:00 am to 11:00 am) 6 and October 7 (4 hours from 9:00 a.m. to 1:00 p.m.) .- The covid-19 pandemic has revealed the immense need to bring the world of science closer to citizens, so we are going to work on this soft skill through this course. We have invited Inés Ortega, scientific communicator of the CIBER BBN, who will talk[...]

29 Sep

The hepl for researchers to commercialise their life science research tools.

CIBER-BBN, partner of NANBIOSIS, has started a new partnership with Ximbio, part of Cancer Research UK, the largest independent funder of cancer research in the world, to facilitate the commercialisation of life science research tools. This new partnership with Ximbio will help CIBER-BBN groups to develop as bussiness the research tools from their labs and units of NANBIOSIS into commercial products, making them easily available for industry and other academics (including those not under patent protection), from sourcing and production, to sales, licensing and responding to enquiries about your reagents. On October 1st, 2021 – 11:00 – 12:30 CEST , with take place the on[...]

24 Sep

Cristina Pérez, Young Investigator Award at the STAFF congress

Cristina Pérez, has been the winner of the Young Researcher Award (YIA) at the STAFF congress held in Sirolo (Italy), from Septembre 1 to 4, for her work entitled “Characterization of impaired ventricular repolarization by quantification of QT delay after heart rate changes in stress test” Cristina Pérez is a researcher from BSICoS. Research Group that coordinates NANBIOSIS ICTS Unit 27 “High Performance Computing”, led by PAblo Laguna (from I3A-UNIZAR and CIBER-BBN) Further information at BSICoS Websit[...]

24 Sep

Diego García, finalist in the Young Researcher Award at the CinC

Researchers from BSICoS Research Group – NANBIOSIS U27 (from I3A-UNIZAR and CIBER-BBN presented their works in the Computing in Cardiology (CinC) Conference, held in Brno (Czech Republic) on 12-15 September. Diego García was Young Researcher Award (YIA) finalist with the work “Ventilatory Thresholds Estimation Based on ECG-derived Respiratory Rate”. The purpose of this work is to study the feasibility of estimating the first and second ventilatory thresholds (VT1 and VT2, respectively) by using electrocardiogram (ECG)-derived respiratory rate during exercise testing. The computation was performed by the ICTS NANBIOSIS, specifically by the High Performance Computing Unit of the CIBER-BBN at the I3A-University of[...]

23 Sep

High quality antibodies for very challenging projects

Researchers of Nb4D group – Unit 2 of the ICTS NANBIOSIS (led by Pilar Marco, from CIBER-BBN and the IQAC-CSIC) have participated in Expoquimia 2021, the International Chemistry Meeting, which took place from 14 to September 17 at the Fira de Barcelona.The researchers presented their work in several projects: the FoodSmartPhone project (MSCA-ITN-720325 action), the QS4CF (RTI2018-096278-B-C21), the QS-Motion (TV32018-201825-30-31) and on the PoC4CoV project (PIE-202050E090; PTI Salud Global, CSIC). Research at the FoodSmartPhone(MSCA-ITN-720325 action) is focus on developing devices for the monitoring of contaminants of interest in food safety through the use of mobile phones. The production of t[...]

20 Sep

The European Researcher’s Night with NANBIOSIS’ scientists.

The European Researchers’s Nigth is a public event dedicated to the dissemination of science that is held every year in more than 300 cities in 30 countries of Europe at the same time, organized on the last Friday and Saturday of September. This year face-to-face activities are progrmmed in different locations of Catalonian cities and also the “Nit de la Recerca” YouTube channel offers more than 20 noves microxerrades led by researchers from Catalonia. Two NANBIOSIS’ researchers have joined this event to explain their research: Julian Guercetti – Nb4D Group – NANBIOSIS U2 CAbS, from IQAC-CSIC and CIBER-BBN, will giv[...]

15 Sep

European Biosensor Symposium digital seminars, co-organized by Pilar Marco

Pilar Marco, the Scientific Director of NANBIOSIS U2 , Custom Antibody Service (CAbS), and leader of the group Nanobiotechnology for Diagnostics (Nb4D) from CIBER-BBN and IQAC-CSIC, coorganises the European Biosensor Symposium digital seminar series. The aim of these seminar series is to continue with the purpose of the European Biosensor Symposium, held in March 2021, to allow especially juior reseachers to present their research, exchange ideas and built networds. The seminars are scheduled on the third Tuesday of every month at 18:00 CET, via zoom. Each of the seminars is organized by a host focussing on a specific topic: “Interferometric sensors“, hosted[...]

11 Sep

Filtered Air Shower for Animal Housing

Cáceres, September 10th, 2021 In the framework of the project “Updating the Infrastructures and implementation of a LIMS document control and management system to enhance the capacities of the Distributed ICTS NANBIOSIS Units managed by the CCMIJU (AILIMS-NANBIOSIS)  a filtered air shower for Animal Housing has been bought with strictly controlled environmental parameters, to prevent possible cross-contamination and the entry of pathogens and viral particles, since during  entry and exit of personnel to this area, contamination by the mentioned particles has been detected, so the air shower is an effective solution to eliminate them and protect the controlled environment. AILIMS[...]

04 Aug

New strategies with nanoparticles to fight the most aggressive breast cancer

Breast cancer is the leading cause of death in women between the ages of 20 and 59, and despite the fact that its diagnosis and treatment have improved greatly in recent years, relapses and resistance to treatment leave some young patients without a therapeutic option. . Tumor stem cells, from which the rest of cancer cells derive and are the cause of the most aggressive cancers, are especially resistant to conventional cancer treatments. In this line, researchers from the CIBER-BBN of the Drug Delivery & Targeting group and NANBIOSIS U20 at the Vall d’Hebron Research Institute (VHIR),, have developed a[...]

30 Jul

Annual CIBER-BBN and NANBIOSIS Conference 2021 – SAVE THE DATE

On 15-16 noviembre 2021 will be hold the annual Conference of CIBER-BBN and NANBIOSIS CIBER-BBN´s Annual Conference is the most awaited yearly event for our research community to gather and discuss over past year´s achievements as well as to be updated about emerging key technologies. Under this light, this year´s edition includes presentations of internal collaborative projects, three plenary talks given by acknowledged experts in the fields of Biosignal Analysis, Hybrid Nanomaterials and Drug Delivery and a session dedicated to COVID-19 and the most recent advances in the fight against it as for detection, prevention and therapy. Due to this[...]

27 Jul

Characterization of encapsulated porcine cardiosphere-derived cells for cardiac regeneration.

Researchers of NANBIOSIS U10 Drug Formulation unit of CIBER-BBN and UPV/EHU and NANBIOSIS U14 Cell Therapy unit and U24 Medical imaging unit at CCMIJU have participated in a research that proposes the use of encapsulated cardiosphere-derived cells (CDC), obtained from heart tissue, as regenerative cell therapy. “The encapsulation of the cells has been carried out in NANBIOSIS Unit 10, as well as the characterization of the cells (both encapsulated and unencapsulated) for their application in regenerative medicine (cardiac regeneration); and unit 14 of NANBIOSIS has obtained the cell model used for the study “ – Explains Kaoutar Ziani Akrirout, researc[...]

20 Jul

Inkjet printing technology is driving innovation of sensors for point-of-care devices

Miguel Zea, researcher at GAB Group –  Nanbiosis U8 Micro– Nano Technology Unit  will defend hir PhD thesis on Friday 23 of July, at 11 am, at the Graus Room of the Faculty of Sciences and Biosciences of the UAB about “Inkjet printing technology is driving the innovation of sensors for point-of-care devices” Thesis directors: Gemma Gabriel and Eloi Ramon Further information and registration for the event, onñine, here Abstract:  The ‘Inkjet printing’ technology is called to be the next generation of flexible electronics capable of performing functions that were only accessible with state-of-the-art microfabrication technologies. This is due, in part, to the versatility of digital,[...]

19 Jul

Radical Dendrimers as Contrast Agents for Magnetic Resonance Imaging

José Vidal Gancedo, researcher from ICMAB-CSIC and CIBER-BBN is leading the project VIRADEN: “In vivo Studies of Radical Dendrimers as Contrast Agents for Magnetic Resonance Imaging“, one of the ICMAB Frontier Interdisciplinary Projects (FIP) 2021. The project aims to evaluate the new contrast agents for MRI based on organic radical dendrimers developed in his group, to substitute the currently used contrast agents based on toxic metals, with the final goal of obtaining useful contrast agents in the early detection of tumors José Vidal has explained NANBIOSIS participation in the project through Biomaterial Processing and Nanostructuring equipments of NANBIOSIS U6 counting wit[...]

14 Jul

Study of new liposomes for the delivery of enzymes through biological membranes

Judit Tomsen, researcher at Nanomol Group – NANBIOSIS U6 (ICMAB-CSIC and CIBER-BBN)  will defend her PhD thesis on Thursday, 15 July 2021, at 11 am in an hybrid session, from the ICMAB Seminar Room “Carles Miravitlles”.  Further information and Registration to attend the PhD Thesis defense via Zoom  at ICMAB-website. Supervisors: Nora Ventosa (Scientific Director of NANBIOSIS U6 Biomaterial Processing and Nanostructuring Unit and leader of Nanomol Group of CIBER-BBN- ICMAB-CSIC Elisabet González, Nanomol Group of CIBER-BBN – ICMAB-CSIC Abstract: Liposomes are lipid-based nanovesicles widely explored as nanocarriers for the transport of biomolecules or drugs of interest to the place of action, and for the development of new[...]

13 Jul

New NANBIOSIS’ focus on Cutting-Edge Biomedical Solutions

We are delighted to announce the publication of our new corporate brochure which reflects NANBIOSIS’s main core competences. This fresh looking promotion material has been intentionally designed to emphasize our experience of join expertise and capabilities solving problems in biomedical research, focussing on quality, adaptability and excellence commitment. The NANBIOSIS’ Cutting-Edge biomedical solutions  have been updated to offer a wider range of Integrated solutions to advanced challenges faced by biomedical researchers in the fields of tissue engineering, regenerative medicine, diagnostic and medical devices. The Cutting-Edge biomedical solutions offered by the ICTS NANBIOSIS have been organised drilling down on our key areas:[...]

12 Jul

Jaume Veciana awarded by the Catalan Society of Chemistry with the Prize to the Scientific Excellence

Jaume Veciana Miró, Director of NANBIOSIS, has been awarded by the Catalan Society of Chemistry in its 2021 edition of Awards in research, education and dissemination with the Prize to the Scientific Excellence for his scientific career.[...]

09 Jul

Online Course in Basic Procedures and Introduction to Mesenchymal Stem Cell Culture

From 30 August 2021 to 29 September 2021 Jesus Usón Minimally Invasive Surgery Centre (JUMISC) has organized an on line course on Procedures and Introduction to Mesenchymal Stem Cell Culture. The course is directected by Francisco Miguel Sánchez Margallo and run by researchers of NANBIOSIS U14 Cell Therapy Unit at JUMISC Stem cells are cells capable of differentiating into a wide variety of cell types and can be isolated from different tissues. They have regenerative and anti-inflammatory properties thanks to the secretion of paracrine factors. Currently, these cells are being widely used in clinical trials for the treatment of different diseases such as[...]

08 Jul

New project ExofluidTT for the production of nanovesicles using microfluidics applicable on Biomedicine

Víctor Sebastián Cabeza, researcher of NANBIOSIS U9 Synthesis of Nanoparticles of CIBER-BBN and the Institute of Nanoscience and Materials of Aragón, INMA, has obtained a research grant in the XX National Contest of the Ramón Areces Foundation in the category of Life and Matter Sciences with a funding of € 112,000 for the development in 3 years of nanovesicles using microfluidic technology. As explained by Victor Sebastian “the characterization of the nanovesicles will be carried with the equiment and expertise of NANBIOSIS Unit 9 The project entitled “Engineering of extracellular vesicles-exosomes using microfluidic technology for its application in biomedicine: ExoFluidTT”[...]

07 Jul

Ibane Abasolo new Scientific Director of unit 20 of NANBIOSIS

Ibane Abasolo, the Scientific Coordinator of NANBIOSIS U20 of the CIBER-BBN at the Vall d’Hebron Research Institute (VHIR), has been appointed new Scientific Director, replacing Simó Schwartz, who has recently assumed the Directorate of the Blood and Tissue Bank of Catalonia. With her, there are 11 women who are Scientific Directors of NANBIOSIS units (46%), with the incorporation of Nora Ventosa and Rosa Villa during the past year 2020. Ibane Abasolo has also been appointed IP of the CIBER group that coordinates unit 20 of NANBIOSIS. The female replacement in the leadership of the CIBER groups is one of t[...]

06 Jul

New Nanomedicines for the topical treatment of complex wounds

Acute and chronic wounds are a growing global health problem. The incidence of non-healing chronic wounds has exponentially increased with the aging of the population and chronic diseases. It has been estimated that there is a 2% prevalence of chronic wounds in the general population, which is associated with an annual estimated cost of more than US$50 billion. Biomaterial-based treatments are helpful in improving small-sized and uncomplicated ulcers. Biologic molecules, named epidermal growth factors (EGFs) have demonstrated potent therapeutic efficacy along with limited side effects, however, exogenous EGF is rapidly cleared from the topical application site. Jaume Veciana, Nora Ventosa[...]

05 Jul

Purchase, installation and implementation of a treatment, distribution and management system for the environmental control and registration of animal housing rooms

There is a growing demand, coming from the scientific community, to carry out studies with animal models in the best conditions for them. For this reason, the need of implementing a new control and recording system of environmental conditions within the stabling rooms of the CCMIJU Animal Housing arises. The whole process and the awarded company, General de Instalaciones y Conservación S.L., have been published in the following link of the Public Sector Contracting Platform, within the framework of the project “Updating of the Infrastructures and implementation of a document control and LIMS management system to enhance the capacities of[...]

24 Jun

Awarded works for improvement and adaptation of the spaces for the maintenance of the experimental models in the CCMIJU’s Animal Housing

The Public Sector Contracting Platform has published the awarding to the company “Depur GM Deseño e Obra S.L” to carry out the improvement works in the CCMIJU’s Animal Housing within the framework of the project “Updating the Infrastructures and implementation of a LIMS document control and management system to enhance the capacities of the Distributed ICTS NANBIOSIS Units managed by the CCMIJU (AILIMS-NANBIOSIS). For further details, please click here The mentioned project has been co-funded by the European Regional Development Fund (FEDER) through the Ministry of Science and Innovation within the framework of the Programa Operativo Plurirregional de España (POPE)[...]

21 Jun

A project by NANBIOSIS researchers, focused on COVID-19 detection and therapy, selected in ‘La Marató’ research program

The Scientific Commission of ‘La Marató TV3’ has seleced the project entitled “Diagnosis and treatment of Sars-Cov-2 by triplex formation”, led by Ramon Eritja, Scientific Director of NANBIOSIS Unit 29 Oligonucleotide Synthesis Platform (OSP) from CIBER-BBN and IQAC_CSIC to be financed with € 398,750.00. Verónica Noé from the Fundació Bosch i Gimpera Universitat de Barcelona, ​​the CIBERESP researcher Enrique Calderón Sandubete, from the Virgen del Rocío University Hospital and María Valeria Grazú Bonavía, from the Institute of Nanoscience and Materials of Aragón, INMA (CSIC- UNIZE) also participate in this project. The edition of this solidarity initiative promoted by the Corporació[...]

14 Jun

New drug delivery system for prolonged pain relief

The management of musculoskeletal pain is a key challenge due to the short duration of anesthetic effect produced by existing clinical treatments, in addition to their potential side effects. Researchers from the CIBER-BBN, the Institute of Nanoscience and Materials of Aragón (INMA), CSIC-University of Zaragoza and the Institute of Health Research of Aragón (IIS Aragón), in collaboration with researchers from the Faculty of Veterinary Medicine of the University of Zaragoza and with participation of NANBIOSIS Unit 9 Synthesis of Nanoparticles Unit, have developed nanogels loaded with nanocrystals of bupivacaine (an anesthetic commonly used in epidural anesthesia and in the contro[...]

03 Jun

Novel nano-encapsulation approach for efficient dopamine delivery in Parkinson’s treatment

UAB Parkinson’s disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters active in the central nervous system. Symptomatic treatment focuses on increasing the concentration of dopamine into the brain.However, dopamine is not directly administered, because it is unable to cross the so called blood-brain barrier, which prevents some of the substances circulating in the blood to penetrate into the nervous system. Thus, DA precursor levodopa (L-DOPA) –an amino-acid which participates[...]

01 Jun

New call for ICTS for the construction, development, instrumentation, equiment and improvement of ICTS capabilities

The Ministry of Science and Innovation has approved a call for ICTS for 37 million euros. Investment lines of the ICTS associated with the construction, development, instrumentation, equipment and improvement of scientific-technical capacities of the ICTS will be financed with the 100% of the eligible cost. This call is funded by the European Union Recovery and Resilience Mechanism. The Singular Scientific and Technical Infrastructures (ICTS) are large, one-of-a-kind facilities, which are dedicated to cutting-edge technological research and development of the highest quality, as well as promoting the transmission, exchange and preservation of knowledge, technology transfer and innovation. They are distributed[...]

27 May

New device for more efficient gluten detection

About 1% of the world’s population suffers from celiac disease, a complex and autoimmune disorder caused by ingestion of gluten and for which there is no treatment beyond its elimination from the diet. In Spain every May 27, the National Celiac Day is commemorated to publicize the disease and give visibility and support to people with celiac disease. The detection of gluten becomes a key element for celiac patients to control the disease, as well as for the food industry, whose regulation requires declaring its presence in food. In this line, a team of researchers coordinated by the professor of[...]

21 May

A new biosensor will help for the early diagnosis of breast cancer

A team of Spanish researchers coordinated by the professor of the Polytechnic University of Valencia (UPV) and scientific director of the CIBER-BBN and NANBIOSIS unit 26, Ramón Martínez Máñez, and the Valencian oncologist, co-coordinator of the Research Group of Biology in Breast Cancer of the INCLIVA Health Research Institute, of the Hospital Clínico de València, Ana Lluch, also belonging to the CIBER de Cáncer (CIBERONC), has developed a prototype of a new biosensor to help detect breast cancer in its phases earlier. The work has been published in ACS Sensors magazine. According to the latest data collected by the European[...]

20 May

A potential solution to decrease toxicity in colorectal cancer treatment

Cancer is one of the world’s leading causes of death, with over 18.1 million cases and 9.6 million deaths in 2018. One of the most successful drugs used in chemotherapy for the treatment of diverse severe cancers is 5-Fluorouracil (5-FU), however, one of the major problems described in clinical practice is 5-FU cell resistance. Resarchers of the Nucleic Acids group and the Colloidal and interfacial Chemistry Group of CIBER-BBN at IQAC-CSIC have collaborated in a research to  inspect and test the ability of parallel G-quadruplexes to deliver floxuridine oligonucleotides into different types of cancer cells; finally, the internalization ability and[...]

16 May

The importance of Nanomedicine and Bioengineering to address health challenges

Josep Samitier, Coordinator of the Nanomedicine Platform (NanoMed) and Director of IBEC, as well as Scientific Director of NANBIOSIS unit 7 of Nanotecnology, of IBEC and CIBER-BBN, particiated in the XIV Annual Conference of Biomedical Research Technology Platforms was held on 11 and 12 May. The Conference counted with the presence of relevant public and private sector actors, and more than 700 registered participants. During the opening ceremony, was opened, among others, by the Minister of Science and Innovation, Pedro Duque, it was precisely emphasized the importance of investment in science and technology. In the words of Josep Samitier: “The healt[...]

12 May

NANBIOSIS participates in a transversal action of CIBER incorporated into the Biobanks and Biomodels Platform of the Carlos III Health Institute

Recently, a transversal action of CIBER has been started, coordinated by Cristina Villena, made up of teams from 4 thematic areas of the CIBER (CIBERES, CIBERER, CIBER-BBN and CIBERONC) that has constituted a unit of the CIBER that has been incorporated into the new Platform of Biobanks and Biomodels of the Carlos III Health Institute (ISCIII). The CIBER unit has been selected in the call for ISCIII Platforms to support R+D+I in Biomedicine and Health Sciences of the Strategic Action in Health 2017-2020, which will finance the Platform of Biobanks and Biomodels and two more platforms on support to clinica[...]

10 May

Collaboration in the CSIC White Paper “New Challenges in Biomedicine and Health”

The Spanish National Research Council (CSIC) is publishing the White Papers of the 14 strategic themes established on the basis of their scientific impact and social importance. The pen access to the White Paper of the fifth Challenge, Brain, Mind & Behaviour, is now avaailable. The book is the result of the “CSIC Scientific Challenges: Towards 2030”, in which the institution tackles the main issues and priorities for the future. This book is coordinated by Jesús Marco de Lucas and M. Victoria Moreno-Arribas. Drs. Rosa Villa and Anton Guimera (Biomedical Applications Group, GAB and NANBIOSIS U8 Micro– Nano Technology Unit from CIBER-BBN and IMB-CNM-CSIC)[...]

05 May

Practical Sessions in the Master of Cosmetic and Dermopharmacy by NANBIOSIS U12

The researchers of NANBIOSIS U12, Nanostructured liquid characterization unit of CIBR-BBN and IQAC-CSIC, will participate in teaching and training students of the Master en Cosmética y Dermofarmacia, organized by Centro de Estudios Superiores de la Industria Farmacéutica (CESIF), from 17 May to 16 June 2021. Cosmetic manufacturing companies are committed to innovation, both in technological development and in the use of components in their formulations, adapting to new trends and user needs. Determination of colloidal stability, surface tension, particle size and rheological behaviour, among many others properties, is essential for the proper characterization and understanding the performance of cosmetic products.[...]

03 May

Collaboration in the CSIC White Paper “New Challenges in Biomedicine and Health”

The Spanish National Research Council (CSIC) is publishing the White Papers of the 14 strategic themes established on the basis of their scientific impact and social importance. The pen access to the White Paper of the fourth Challenge, New Challenges in Biomedicine and Health, is now avaailable. The book is the result of the “CSIC Scientific Challenges: Towards 2030”, in which the institution tackles the main issues and priorities for the future. This book is coordinated by Mario Delgado (Instituto de Parasitología y Biomedicina “López – Neyra”, Granada) and María Moros (Instituto de Nanociencia y Materiales de Aragón, Zaragoza). Drs. Rosa Villa (Biomedical Applications Group, GAB and[...]

29 Apr

Five experts explain the results of the CSIC Global Health Platform after a year of research on the SARS-CoV-2 coronavirus

– Margarita del Val, Pilar Marco, Mario Mellado, Diego Ramiro and Iñaki Comas will disseminate, in a webinar through YouTube, the works on the disease, diagnosis and social impact– The platform investigates the new coronavirus in six areas: prevention, disease, containment and diagnosis, treatment and vaccines, social impact and communication Five experts from the Higher Council for Scientific Research (CSIC) will explain in a webinar broadcast on YouTube, on Wednesday, May 5 at 6:00 p.m., the results of a year of research at the CSIC on the SARS-CoV-2 coronavirus carried out by the Global Health Platform. In the session, titled[...]

29 Apr

Course on Introduction to Research and Laboratory Techniques in Biosciences

CCMIJU has organised the IV Course on Introduction to research and laboratory techniques in Biosciences, which wil take place at JUMISC from May, 3th to June 6th 2020 under the Direction of Javier García Casado, Scientific Director of NANBIOSIS U14 Cell Therapy and Francisco Miguel Sanchez Margallo Deputy Scientific Director of NANBIOSIS. Other researchers of NANBIOSIS Units offer their expertise as Beatriz Moreno Lobato, Scientific Diector NANBIOSIS U19 and Luis Dávila Gómez, Scientific Director of NANBIOSIS U22. The course include: KNOWLEDGE PILLS FOR RESEARCHEXERCISES AND CASE STUDIES IRNA and DNA: GENE EXPRESSION AND GENETIC STUDIES IN REPRODUCTION.EXERCISES / CASE STUDIES IIPROTEINS AND PROTEOMA: PROTEIN EXPRESSION STUDIES AND PROTEOMIC[...]

28 Apr

First Dresselhaus Prize of the SCN2 to María Jesús Ortiz

María Jesús Ortiz i Aguayo, graduate in Chemistry from the Autonomous University of Barcelona (UAB), has been the winner of the First Dresselhaus Prize, organized by the Catalan Society of Nanoscience and Nanotechnology (SCN2), of the 2020 edition. The award recognizes the work “Development of a pH microsensor for the determination of hydrogen sulfide based on Inkjet Printing“, supervised by Maria del Mar Baeza Labat (UAB) and Gemma Gabriel Buguña, from the Biomedical Applications Group GAB and NANBIOSIS U8 Micro– Nano Technology Unit from CIBER-BBN and IMB-CNM-CSICThe student also did her TFG with Dra. Gemma Gabriel at the IMB-CNM. T[...]

27 Apr

Supply, installation and implementation of a document control system, LIMS management and equipment, to enhance the capacities of the distributed ICTS Units (NANBIOSIS -AILIMS).

The project “Updating the Infrastructures and implementation of a LIMS document control and management system to enhance the capacities of the Distributed ICTS NANBIOSIS Units managed by the CCMIJU (AILIMS-NANBIOSIS) ‘has been co-funded by the European Regional Development Fund (FEDER) within the framework of the Pluriregional Operational Program of Spain (POPE) of Singular Scientific and Technical Infrastructures (ICTS) 2014-2020. The following actions are considered in the framework of the project: -Within Unit 22 or Animal Facility, the Installation and development of an environmental treatment-control system of the housing rooms, an Improvement and adaptation of the spaces for experimental models, t[...]

25 Apr

Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis

Elena Alcalde‑Estévez, Patricia Sosa, Ana Asenjo‑Bueno, Patricia Plaza, Gemma Olmos, Manuel Naves‑Díaz, Diego Rodríguez‑Puyol, Susana López‑Ongil & María P. Ruiz‑Torres, are the authors of an article recently published in the Journal Scientific Reports, of Nature Research, ·mentioning the collaboration in the investigation of the ICTS “NANBIOSIS” U17 Confocal Microscopy Service of CIBER-BNN and the University of Alcalá. Uremic toxins (UT) increase in the serum in parallel with a decrease in the glomerular filtration rate and the development of sarcopenia in patients with chronic kidney disease (CKD). This study analyses the role of UTs in sarcopenia associated with CKD in different[...]

20 Apr

Elena Aznar Gimeno (NANBIOSIS U26) leads a CIBER-BBN transfer project.

The CIBER-BBN transfer program, with its call for transfer projects, has selected two projects for next year with the aim of promoting the transfer of scientific or technological results, derived from the research carried out by the CIBER-BBN groups, to the industrial sector. One of these projects selected is directed by Elena Aznar Gimeno, researcher from the group led by Ramon Martínez Máñez at the IDM-Polytechnic University of Valencia, together with an external group led by Javier Pemán García, from the La Fe Health Research Institute From Valencia. The project has been jointly financed by CIBER-BBN and a company interested[...]

18 Apr

Collaboration of two NANBIOSIS units in the Valorisation Project “ADVERT”

The Project ADVERT (Advanced Extracellular Vesicles for Enzyme Replacement Therapy) is a research valorisation project recently granted by CIBER. The project pursues to advance the development of extracellular vesicles as treatments for lysosomal diseases, specially to bring new therapies to treat FABRY disease. The ADVERT Project will count on the active particpation of two NANBIOSIS units of CIBER-BBN: Unit 20 of the ICTS NANBIOSIS at Vall d’Ebrón Hospital, led by Ibane Abasolo, who coordinates the project. Unit 1 Protein Production Platform (PPP), at the IBB-UAB, led by Neus Ferrer, throught the coordination in the project of José Luis Corchero. T[...]

16 Apr

Participation of NANBIOSIS U25 in the Valorisation Project MR-INITIATE

The Unit 25 of the ICTS NANBIOSIS will be enrolled, through its scientific coordinator Ana Paula Candiota, in a research valorisation project recently granted by CIBER: “Noninvasive MR-based ImagiNg of Immune sysTem action during glIoblastomA TreatmEnt (MR-INITIATE)” Such project has the aim to increase the TRL of therapy response follow-up methods in glioblastomas, using technological approaches performed at  U25 of NANBIOSIS NMR: Biomedical Applications I The project will be financed with € 20,000. The CIBER-BBN transfer program The CIBER-BBN transfer program through its call for transfer and valorization projects has been designed to promote the transfer to the industrial sector[...]

15 Apr

Launching the Preliminary Market Consultation Webinar of the TREMIRS Project: Minimally Invasive Robotic Surgical Systems

Cáceres, April 15th, 2021 The CCMIJU, as a beneficiary of the Innovative Public Procurement Program of the Ministerio de Ciencia e Innovación, through the project “Minimally Invasive Robotic Surgery Systems” (TREMIRS), will invest € 7,345,300 in the development of innovative solutions in surgical robotics to improve services provided to the patient, the surgeon’s ergonomics and offer greater benefits to the surgical team, thus achieving an increase in the quality of healthcare. This ambitious challenge, 80% co-funded by the European Regional Development Fund under the Programa Operativo Plurirregional de España (POPE) 2014-2020 and by the Consejería de Economía, Ciencia y Agenda[...]

09 Apr

New organ-on-chip models provide new information for targeted treatments in personalised medicine

Xavi Illa, Gemma Gabriel, Mar Alvarez and Rosa Villa, researchers of NANBIOSIS ICTS U8 Micro– Nano Technology Unit (from CIBER-BBN and the IMB-CNM-CSIC). are co-authors of two reviews that summarise the latest efforts in organ-on-chip technologies to emulate in vitro microfluidic systems. These devices are an opportunity to evolve the fields of biofabrication and sensing technology. Organ-on-chip (OOC) technology has been an efficient tool in modern research to substitute laboratory mice and simulate tissue and organ-level physiology and function. In particular, these in vitro devices have been extensively applied to model the intestine, enhancing the research community’s knowledge about intestina[...]

07 Apr

Toxicity evaluation on non-target organisms with the collaboration of NANBIOSIS U17 Confocal microscopy

Sara Jiménez-Jiménez, Georgiana Amariei, Karina Boltes, María Ángeles García and María Luisa Marina have recently published an article in the Journal of Chromatography A, ·mentioning the collaboration in the investigation of the ICTS “NANBIOSIS” U17 Confocal Microscopy Service of CIBER-BNN and the University of Alcalá. The echocytotoxicity of racemic panthenol and dexpanthenol at different concentrations and exposure times in Spirodela polyrhiza has been studied using NANBIOSIS U17 Confocal Microscopy Service “Panthenol (racemic mixture) and its isomer dexpanthenol have been classified as toxic for the aquatic environment by the European Regulation (EC 1272/2008). These studies are based on the natural emission[...]

06 Apr

A GLOBAL VISION OF THE COVID-19 PANDEMIC by CSIC

A report from the Spanish National Research Council (CSIC) collects in open access the results of a year of research on SARS-CoV-2. The book ‘A global vision of the COVID-19 pandemic’ shows the responses and solutions obtained by the 300 research teams of the CSIC Global Health Platform. The Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) has participated in the preparation of the chapter ‘Actions in containment and diagnosis’: Specific mucosal protection against the entry of SARS-CoV-2 – Lluisa Coderch. The role of diagnosis in the face of the pandemic – by M.-Pilar Marco, Scientific Director of NANBIOSIS U2 Custom[...]

26 Mar

A new european infrastructure will facilitate the transfer of nano-pharmaceuticals from the lab to the clinic

Launch of the cross-european PHOENIX project, which will provide a new infrastructure available to research laboratories, SMEs and start-ups to facilitate the transfer of nano-pharmaceuticals from the laboratory to clinical practice. PHOENIX will have a duration of 4 years and a total budget of 14.45 million euros. Two CSIC Institutes, ICMAB (CSIC) and INMA (CSIC-UNIZAR), and one CSIC spin-off, Nanomol Technologies, participate in the project, will count with the expertise of NANBIOSIS unit 6 (from CIBER-BBN and ICMAB-CSIC), led by Nora Ventosa. PHOENIX is an innovation project funded by EU’s Horizon2020 Framework Programme aimed to provide services for the development, characterization, testing,[...]

21 Mar

In search of antimicrobials from natural bee products to coat implantable biomaterials, avoiding resistance.

The Microbial Adhesion research group-NANBIOSIS ICTS U16 Surface Characterization and Calorimetry Unit of the University of Extremadura (AM-UEX)-, belonging to the CIBER-BBN, led by Maria Luisa González, is searching in natural products, specifically in propolis, compounds with antimicrobial activity to help fight infections associated with biomaterials.Medical devices have greatly improved healthcare. But biofilm-associated infections related to the use of these devices are a major clinical concern. Biofilms are understood as bacterial communities that adhere to the surface of the devices and are embedded in a polymeric matrix that they themselves produce. This supracellular social organization arises as a survival strategy[...]

20 Mar

Extracellular vesicles as vehicles for therapeutic enzymes in lysosomal deposition diseases

Researchers of two CIBER-BBN units of the ICTS (Singular Scientific and Technical Infrastructures) NANBIOSIS, led by Ibane Abasolo the U20 located in the VHIR and the U6 in ICMAB-CSIC have participated in a study to improve the treatment of lysosomal disorders. In recent years, enzyme replacement therapies (ERTs) based on the systemic administration of a functional version of the defective enzyme have gained clinical relevance as a treatment for lysosomal storage disorders (LSD). However, the systemic administration of these recombinant enzymes has negative aspects, such as their low stability and inadequate distribution to the affected organs that result in a[...]

18 Mar

The relevance of biomedical signal processing in the understanding of biological systems

Within the framework of NeoCom2021 Jesús Lázaro, researcher of BSICoS group and NANBIOSIS U27 High Performance Computing form CIBER-BBN and I3A-UZ will explain how biomedical signal processing can be used to improve the current understanding of the functioning of biological systems, conditions related to the cardiovascular, respiratory, and autonomic nervous systems, as well as their interactions. Prof. Lázaro will review the progress of the WECARMON European Project whose objective is the development of a system for long-term monitoring (months / years) of patients with cardiorespiratory diseases. NEOCOM: As every year, the Territorial Demarcation of the COIT in Aragon and t[...]

16 Mar

Development of a protein-only drug delivery system for sustained release

The Nanotoxicology Unit of CIBER-BBN ICTS NANBIOSIS (u18-nanotoxicology-unit), led by Ramon Mangues at the Research Institute of the Hospital de Sant Pau and the NABIOSIS (nanbiosis.es)Protein Production Platform (u1-protein-production-platform-ppp) led by Antonio Villaverde and Neus Ferrer Miralles of the Institute of Biotechnology and Biomedicine at the Autonomous University of Barcelona, have participated in the development of a novel drug delivery system able to achieve sustained release of proteins with intrinsic antitumor activity. This delivery system consists on inclusion bacterial bodies formed by recombinant fusion proteins that precipitate while being expressed in bacteria, acquiring an amyloid structure, but remaining functional. Thus,[...]

15 Mar

A new generation of devices for the rapid, cheap and easy diagnosis of candidemia.

Candidemia is an infection caused by fungi of the genus Candida that is associated with high complication rates with a mortality that can reach 40%. A group of researchers have managed to develop a new material that allows for the rapid detection of candidaemia, with a sensitivity that exceeds 90% and a specificity greater than 95%. Researchers from the CIBER-BBN (Center for Biomedical Research for Bioengineering, Biomaterials and Nanomedicine). the Polytechnic University of Valencia (UPV) and the La Fe Health Research Institute (IIS La Fe), with the participation of Unit 26 of NANBIOSIS NMR Biomedical Applications II, in collaboration wit[...]

13 Mar

CAMPUS JUMISC online training

The Jesús Usón Minimally Invasive Surgery Center, CCMIJU, partner of NANBIOSIS, offer high quality training based on itslearning philosophy perfectly adapted to new teaching methodologies and to a more dynamic and interconnected world. The CCMIJU Campus responds to the new modalities of online training and education. Based on their interests and objectives, students choose the course to suit their level and learning pace, being able to interact with expert tutors through social networks. Emerging as a complement to face-to-face activity, the CCMIJU Campus offers high quality training adapted to new methodologies, and to a more dynamic and intercommunicated world. T[...]

11 Mar

Modulation of intercolumnar synchronization by endogenous electric fields in cerebral cortex with neuroprobes by NANBIOSIS unit 8

The collaboration of NANBIOSIS U8 Micro–Nano Technology Unit of the CIBER in Bioengineering, Biomaterials & Nanomedicine (CIBER-BBN) at the IMB-CNM in the research carried out by scientist of Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Université Paris-Saclay, Centre National de la Recherche Scientifique (CNRS) and ICREA has bien acknowledged in the publication of the results by Science Advances. Rosa Villa and Xavi Illa have been in charge of the fabrication of the probes used, more specifically, neuroprobes were designed and manufactured with 16 Ti / Au microelectrodes (20 / 200nm) on flexible polyimide substrates with open areas to improv[...]

10 Mar

Simo Schwartz: new General Director of the Bank of Blood and Tissues of Catalonia.

Simó Schwartz Jr., Scientific Director of NANBIOSIS Unit 20 In Vivo Experimental Platform has been appointed as the new general director of the Bank of Blood and Tissues of Catalonia, replacing Enric Argelagués, who is leaving his post after 17 years as director. Argelagués was the promoter of the unification of blood banks that began in the eighties and culminated in the current Bank of Blood and Tissues of Catalonia. Simó Schwartz now assumes the executive management of the organization, which currently has more than 800 workers and its mission is to ensure that all people in Catalonia have t[...]

04 Mar

Reversing pulmonary fibrosis has been achieved in murine models with peptide-loaded nanoparticles

A new study with participation of NANBIOSIS Unit 10 Drug Formulation unit of CIBER-BBN and UPV/EHU, has succeeded in preventing and reversing pulmonary fibrosis in experimental models with PLGA / PEI nanoparticles loaded with the GSE4 peptide. These results are the first step to study its possible antifibrotic effect in patients with idiopathic pulmonary fibrosis and other progressive fibrosing diffuse interstitial lung diseases that present altered telomere function. NANBIOSIS unit 10 has been responsible for the design and manufacture of biodegradable nanoparticles loaded with the peptide. The work is led by Rosario Perona and Leandro Sastre, researchers of CIBERER at[...]

03 Mar

Graphene sensors read low-frequency neural waves associated with distinct brain states

Xavier Illa, Anton Guimrea y Eduard Masvidal, researchers of the CIBER-BBN group GAB Lab at IMB-CNM led by Rosa Villa, are coauthors of a study recently published in “Nature Communication”, in which it is demonstrated that graphene-based active sensor arrays are a mature technology for large-scale application in wide frequency band neural sensing interfaces. NANBIOSIS U8 Micro– Nano Technology Unit has been used in the development of the research. This research has been carruied out within the framework of the European Project “Graphene Flagship. The scientists have developed a sensor based on CVD graphene that detects brain signals in a wide frequency[...]

01 Mar

CCMIJU leads an European Project based on mixed reality and 3D printing applied to medical education

The CCMIJU, partner of NANBIOSIS leads a European consortium of 9 partners from Spain, Norway, Netherlands, Romania and Greece to carry out the Research Project entitled “Mixed Reality in Medical Education Based on Interactive Applications“-MIREIA, funded by the Erasmus+ Programme – Key Action 2 (KA2): Cooperation for innovation and the exchange of good practices – Knowledge Alliances. The consortium members will work together to develop an innovative methodology and tools to provide paedagogical content for customized training based on 3D models, such as anatomical models (with and without pathologies) built from real-patient cases (e.g. medical imaging studies) or virtual scenarios for basic training in[...]

26 Feb

A more effective nanomedicine has been developed for the treatment of Fabry rare disease.

28 February: International Rare Disease Day This is one of the major achievements of the European Smart4Fabry project, which is now coming to an end after four years of work.The results have been made possible by nanotechnology and the approach developed could be applied to other drugs in the future.The new drug improves on current treatments and helps reduce costs and improve patients’ quality of life. Barcelona, 26 February 2021.- The advance of nanomedicine opens up new possibilities in the development of drugs, such as the one recently developed for the rare disease Fabry, with improved efficacy compared to existing[...]

25 Feb

An Auristatin-based nanoconjugate reduces leukemia burden in a disseminated AML model

Researchers of the Nanotoxicology Unit of the the CIBER-BBN ICTS NANBIOSIS (u18-nanotoxicology-unit), leaded by Ramon Mangues and Isolda Casanova at the Research Institute of the Hospital de Sant Pau and of the NANBIOSIS (nanbiosis.es) Protein Platform (u1-protein-production-platform-ppp) leaded by Antonio Villaverde and Neus Ferrer Miralles of the Institute of Biotechnology and Biomedicine at the Autonomous University of Barcelona, have developed a novel protein-Auristatin nanoconjugate that specifically targets CXCR4-overexpressing acute myeloid leukemia (AML) cells. It selectively accumulates in target cancer cells expressing this receptor and deliver the toxin Auristatin within their cytosol. There, Auristatin potently blocks microtubule polymerization, provoking mitotic catastrophe,[...]

23 Feb

New COVID-19 Diagnostic System Ready for Trials in Clinical Samples

The new system for the rapid, economic and efficient diagnosis of COVID-19 devised by the Universitat Politècnica de València (UPV), the IIS La Fe and the CIBER-BBN is now ready for trials on clinical samples. Since the pandemic broke out, the group of Professor Ramón Martínez Máñez, a researcher at the IDM Institute of the UPV and scientific director of the CIBER-BBN and NANBIOSIS U26 RNM for Biomedical Applications I, has been working on an alternative for the diagnosis of COVID-19, based on nanoporous films. These materials are capable of storing an indicator that is released only in the presenc[...]

21 Feb

A nanotoxin targeting the receptor CXCR4 blocks lymphoma dissemination

Researchers at the Nanotoxicology Unit of CIBER-BBN ICTS NANBIOSIS (u18-nanotoxicology-unit), led by Ramon Mangues and Isolda Casanova of the Research Institute at the Hospital de Sant Pau and the Researchers of the NANBIOSIS (nanbiosis.es) Protein Production Platform (u1-protein-production-platform-ppp) led by Antonio Villaverde and Neus Ferrer Miralles of the Institute of Biotechnology and Biomedicine at the Autonomous University of Barcelona, have participated in the development of a novel protein nanoparticle that incorporates the Exotoxin of the bacteria Pseudomonas aeruginosa, capable of targeting lymphoma cells that overexpress the CXCR4 receptor. They internalize selectively in target cancer cells through CXCR4 receptor-mediated endocytosis du[...]

18 Feb

Gels formed from the interaction of lipid vesicles: Influence of charge in their structural and rheological properties

Susana Vilchez, researcher at NANBIOSIS U12. Nanostructured liquid characterization unit  of CIBER-BBN and IQAC-CSIC, is coauthor of an article recently published in the Journal of Molecular Liquids. “This work – explains Susana Vilchez – shows how structural and viscoelastic properties of a lipid colloidal gel can be altered by varying the ratio of charged lipids in the dispersion. These findings corroborate that the eventual formation of the gel and the morphology of its network is governed by the repulsive potential of the particles instead of the molecular composition of their membranes. Thus, the right control of charge balance in the system may[...]

16 Feb

Agreement signed with Spanish Government for the allocation of FEDER funds for NANBIOSIS ICTS units at JUMISC

In the framework of the FEDER Program in ICTS  2019 14 50, a project related to the ICTS NANBIOSIS has been selected by the Ministry of Science, Innovation and Universities for co financing with FEDER funds of the European Regional Development Funds program. An agreement has been signed between Ministry of Science and Innovation and CCMIJU, institution for the co financing of the Project ICTS 2019 14 50 : Genética embrionaria en reproducción asistida (GENERA NANBIOSIS) in Unit 23. The total budget of the project amounts to € 98.000, with 80% financing with FEDER Funds. CCMIU is processing the necessary[...]

15 Feb

Identification of a novel nanotherapy active in cancer cells resistant to chemotherapy

Researchers of the Nanotoxicology Unit (u18-nanotoxicology-unit) led by Ramon Mangues and Isolda Casanova at the Research Institute of the Hospital de Sant Pau and the Protein Production Platform (u1-protein-production-platform-ppp), led by Antonio Villaverde and Neus Ferrer Miralles of the Institute of Biotechnology and Biomedicine at the Autonomous University of Barcelona, both belonging to the ICTS NANBIOSIS (nanbiosis.es) of the CIBER-BBN, have participated in the production of a novel Nanotoxin capable of selectively killing cancer cells which became resistant to chemotherapy. Development of cancer resistance frequently associates with the overexpression of the CXCR4 receptor. It is known that chemotherapy kills cancer[...]

11 Feb

NANBIOSIS Scientific Women in the International Day of Women and Girls in Science

Today February 11 is the International Day of Women and Girls in Science, a day to raise awareness of the gender gap in science and technology. According to the United Nations, while yet women and girls continue to be excluded from participating fully in science, science and gender equality are vital to achieve the internationally agreed development goals, including the 2030 Agenda for Sustainable Development. Thus, in recent years, the international community has made a great effort to inspire and promote the participation of women and girls in science. NANBIOSIS wants to acknowledge  the efforts made by scientific women who struggle every day to contribut[...]

09 Feb

Agreement signed with Spanish Government for the allocation of FEDER funds for Nanbiosis ICTS

In the framework of the FEDER Program in ICTS 2014-2020, a projects related to the ICTS NANBIOSIS has been selected by the Ministry of Science, Innovation and Universities for co-financing with FEDER funds of the European Regional Development Funds program. An agreement has been signed between Ministry of Science, Innovation and CCMIJU, institution that houses NANBIOSIS  U14, U19, U21, U22, U23, U24 for the co-financing of the Project ICTS-2019-14-46: “ACTUALIZACIÓN DE LAS INFRAESTRUCTURAS E IMPLEMENTACIÓN DE UN SISTEMA DE CONTROL DOCUMENTAL Y DE GESTIÓN LIMS PARA POTENCIAR LAS CAPACIDADES DE LAS UNIDADES DE LA ICTS DISTRIBUIDA NANBIOSIS (AILIMS-NANBIOSIS)”  The tota[...]

04 Feb

Nanoparticles to eradicate Cancer Stem Cells

Colorectal cancer (CRC) has a high prevalence worldwide and resistance to conventional chemotherapies and tumor relapse are usually related with a population of cells with malignant properties – Cancer Stem Cells (CSC). Scientists of CIBER-BBN and VHIR have led a research with the goal not only to treat the primary CRC, but also eradicate CSC. For both purposes, the use of nanoparticles (NP) is a useful strategy. These “bullets” carrying a drug in its core, are able to reach tumor tissue due to its small size. Cancer cells, and in particular CSC, present at their surface receptors that could be specifically recognized[...]

04 Feb

Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles

In the frame of the collaboration of three units of NANBIOSIS, researchers of CIBER-BBN Groups proposed a strategy to simultaneously deliver anticancer drug pairs, composed by a tumor-targeted protein nanoparticle and an antiproliferative drug, with specific activ-ity for the same type of cancer. These three units are: NANBIOSIS U1 Protein Production Platform (PPP), at IBB-UAB, led by Toni Villaverde y Neus Ferrer NANBIOSIS U18 of Nanotoxicology Unit, at Institut de Recerca. Hospital de la Santa Creu i Sant Pau, led by Ramón Manques and Isolda Casanova, and NANBIOSIS U29 Oligonucleotide Synthesis Platform (OSP) at IQAC_CSIC, led by Ramón Eritja and[...]

01 Feb

12th Workshop on Magnetic Resonance Spectroscopy and Imaging (MRI/MRS) Applied to Laboratory Animals

We are glad to inform that registration is now open for the 12th Workshop on Magnetic Resonance Spectroscopy and Imaging (MRI/MRS) Applied to Laboratory Animals, organized by the Biochemistry and Molecular Biology Department (UAB) and the Nuclear Magnetic Resonance Facility, which is also part of the NANBIOSIS ICTS U25 NMR: Biomedical Applications I. Workshop will take place February 15-18th, 2021.This course combines a comprehensive series of lectures on the technology of Magnetic resonance spectroscopy and imaging (MRS/MRI) with hands-on laboratory sessions to provide practical demonstrations of key concepts and procedures for preclinical studies.Whether you are considering MRI as a researc[...]

31 Jan

New spin off of VHIR “BSURE Medical” led by Simó Schwartz (NANBIOSIS U20)

Dr. Simó Schwartz, Scientific Director of NANBIOSIS U20 and head of the “Drug Delivery and Targeting group” of CIBER-BBN and VHIR, toghether with Dr. Jaume Alijotas (VHIR), have promoted the creation of the Spin-off ·BSURE Medical· for the devlopment of products and services for the diagnosis, prevention and consultation of aspects related to treatments with all types of bioimplants. One of the objectives of the Drug Delivery and Targeting group is to carry out preclinical studies to determine the effects and toxicities of drug delivery systems, cell therapies and biomaterials. Studies chace been carried out through the Nanbiosis unit U20,[...]

28 Jan

Encapsulation of BSA/alginate water–in–water emulsions by polyelectrolyte complexation

Researchers of NANBIOSIS U12. Nanostructured liquid characterization unit from CIBER-BBN and IQAC-CSIC have recently published an article entitled Encapsulation of BSA/alginate water–in–water emulsions by polyelectrolyte complexation in the scientific journal Food Hydrocolloids The research which results are published involves the encapsulation of drops of water-in-water emulsions, which could be used as vehicles for the administration of active principles. Characterization of emulsions and capsules was performed in the Unit 12 of NANBIOSIS Nanostructured Liquid Characterization Unit. Water-in-Water (W/W) emulsions were prepared in aqueous mixtures of an anionic polyelectrolyte (sodium alginate, NaAlg), with a globular protein (bovine serum albumin, BSA). This combination showed phase separation[...]

27 Jan

Smart-4-Fabry final workshop

Next Wedneday, February 3, 2021 will take place the on-line event Smart-4-Fabry Final Workshop.   Smart-4-Fabry is a european project, coordinated by CIBER-BBN wich has been developed during four years. This project is a sign of cooperation at European level to boost nanomedicine development and translation to clinical stages. This project is also a clear example of the relevance of access to advanced research infrastructures as NANBIOSIS -ICTS. Four NANBIOSIS units have collaborated and contributed to Smart-4-Fabry development: U1 Protein Production Platform (PPP) at IBB-UABU3 Synthesis of Peptides Unit at IQAC-CSICU6 Biomaterial Processing and Nanostructuring Unit at ICMAB-CSICU20 In Vivo[...]

26 Jan

New Center for Research in Advanced Pharmaceutical Development

The NanoBioCel Research group, led by Jose Luis Pedraz, from CIBER-BBN and UPV/EHU, group that coordinates the Unit U10 Drug Formulation of NANBIOSIS -ICTS, together with the Provincial Council of Álava and the Center for Technological Research and Development TECNALIA, have launched last Thursday, January 21, the new Center for Research in Advanced Pharmaceutical Development, which will be located in the Lascaray Building, on the Álava campus of the UPV / EHU. The objective of this center is to introduce new technologies in the pharmaceutical field and promote applied research in 3D Bio-printing, 3D Printing of medical devices and 3D[...]

25 Jan

Electrocardiogram-Derived Tidal Volume During Treadmill Stress Test

Researchers of BSICoS Group and NANBIOSIS ICTS U27 High Performance Computing from CIBER-BBN and I3A-UZ have published a new article in the scientific journal IEEE Transactions Biomedical Engineering. proposing a new method to estimate tidal volume during stress test based only on the electrocardiogram signal. Electrocardiogram (ECG) has been regarded as a source of respiratory information with the main focus in the estimation of the respiratory rate. Although little research concerning the estimation of tidal volume (TV) has been conducted, there are several ECG-derived features that have been related with TV in the literature, such as ECG-derived respiration, heart rate variability or respiratory rate. In this work, resarchers[...]