The service includes de use of singular equipment for optical in vivo imaging (IVIS® Spectrum and Macrofluo) for the acquisition and quantification of bioluminescent and/or fluorescent images in vitro, in vivo or ex vivo.
Quantification services, as well as support on the analysis of obtained images by specialized personnel is also included.
The unit/platform has strong background in oncology and counts with different type of cancer mouse models, all of them monitorable by means of bioluminescence imaging. They include subcutaneous models in a great variety of cancer types (prostate, colon, breast, pancreas, kidney, etc.) and also orthtopic and experimental metastasismodels.
The unit/platform can also set-up and validate novel xenograft models upon request.
List of available models
Planing, execution and interpretation of in vivo assays requirestime and expertise. At this unit, we give consultancy serviceson preclinical model design, support and advice for research projects, including selection and use of the appropriate imaging system and evaluation and interpretation of the data obtained.
The unit/platform is specialized in oncology and lysosomal storages diseases, and several animal models are available for this type of diseases.
However, we are experienced in developing new efficacy models for testing novel nanomaterials, carriers and therapeutica compounds. Please contact us to see how we can help you in your research Project.
Potential target toxicity of new nanomaterials and drug delivery systems has to be carefully evaluated to support further clinical assays. At U20 we can design, perform and evaluate all type of toxicological studies, including those toxicity analyses performed along with efficacy studiestomore specifically designed long-term or short-term toxicity assays.
Specifically, we provide full services of anatomical pathology, from sample preparation, inclusion, section and staining to anatomopathological evaluation.
It houses different animal species, whether small or big (rats, mice, rabbits, dogs, pigs, sheep, etc), in compliance with the physical and legal conditions for experimental research.
