+34 679 490 537info@nanbiosis.com

Preclinical validation bioimaging - Equipment

Preclinical validation bioimaging

U20-E03. Animal Facility

Animal Facility:

The VHIR’s Animal Facility includes areas for rodents, rabbits, pigs, minipigs and sheeps. In the case of rodents the facility includes:
– Standard clean area and passive quarantine with an area of 136 m2 with
-10 holding rooms for 225 rats and 11,200 mice
-1 passive quarantine and isolation room with modern microisolators and capacity for 560 mice
-6 handling areas for carrying out experimental and surgical procedures with supplies of gases and inhalable anesthesia as well as surgical microscopes
– A Barrier area with 65 m2 for housing and handling of specific pathogen free (SPF) animals, including immunodeficient mice
-The Molecular Imaging Platform Room, where the molecular imaging equipment is located

Read More

U20-E02. Equipment for histological processing

Equipment for histological processing:

The facility has the equipment necessary for fixation(chemical or by freezing), preparations of blocks, slicing and staining using various techniques, from conventional to immunohistochemical stains. The set-up includes everything from the automatic tissue processor to a paraffin embedding station, two microtomes, anautomated staining systems and a microscope for digital registration of the samples.

Read More

U20-E01. Optical imaging equipment

Optical imaging equipment:

– Xenogen IVIS ® Spectrum: is a high sensitivity, low background noise system for non-invasive optical imaging which enables bioluminescence and fluorescence imaging of cells (in vitro), entire animals (in vivo) and organs (ex vivo).

– Leica MacroFluo™: is a precision macroscope with filters for multiple fluorochromes, a Z16 APO (16:1) zoom system and a CCD camera to monitor and record the fluorescence of entire organs and tissues at high resolution with no need to process them histologically.

Read More

U22-E06. Room for receipt and handling of animals

One hall for the reception and handling of animals.

Read More

U22-E07. Quarantine rooms pre-experimental process

2 quarantinerooms pre-experimental process

Read More

U22-E08. Room to perform small procedures and cures and preparation rooms for large animals prior to the surgical area

Room to perform small procedures and cures and preparation rooms for large animals prior to the surgical area

Read More

U22-E05. Multi-use rooms for rodents and lagomorphs maintenance

Four multi-use rooms for maintenance of rodents and lagomorphs.
Lagomorphs can individually accommodate upto 102 rabbits.

Read More

U22-E04. Integrated operating room with in the barrier area

One barrier zone for rodents maintenance under SPF conditions with capacity for about 3,000 animals in microisolators. It has autoclaves, SAS to the material inlet, automatic beverage system by reverse osmosis, laminar flow hoods for animal handling and integrated operating room within the barrier zone.

Read More

U22-E03. Barrier zone for maintenance of rodentsunder SPF conditions

One barrier zone for rodents maintenance under SPF conditions with capacity for about 3,000 animals in microisolators. It has autoclaves, SAS to the material inlet, automatic beverage system by reverse osmosis, laminar flow hoods for animal handling and integrated operating room within the barrier zone.

Read More

U22-E01. Rooms for the maintenance of large animals

This unit has facilities with a perimeter area of 3,200 m2 and it has large rooms to house the experimental animals according to their species characteristics. Among the equipment and facilities include:
9 rooms for large animals (pigs) maintenance with capacity for about 350 animals, for long periods of time and environmental, nutritional and microbiological conditions controlled.

Read More