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JUMISC

JUMISC

II Course on introcuction to research and laboratory techniques in biomedicine

JUMISC has organised the Course on introcuction to research and laboratory techniques in biomedicine which wil take place during the month of July, co-Directed by Francisco M. Sanchez Margallo, Deputy Scientific Director of NANBIOSIS  and Javier García Casado, Scientific Director of NANBIOSIS unit 14 Cell Therapy.

Further information and programe: here

Inscriptions: here

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JUMISC will carry out PCR test for COVID-19 infections

The Institute of Health Carlos III (ISCIII), depending of the the Ministry of Science and Innovation, has validated thirty new centers for carrying out PCR tests for COVID-19 infections throughout Spain. The Minimally Invasive Surgery Center, together with the University of Extremadura (JUMISC), partner of NANBIOSIS, will carry out these PCR tests in the laboratory of the veterinary faculty of Cáceres, as it is a P2 biosafety laboratory that is already approved.

They will have the capacity to perform 200 daily PCRs and will work with the samples that the the Extremadura Health Service will send them.

In total, Spain has 54 laboratories to practice the tests that determine COVID-19 infections.

Laboratories validated to carry out these PCR tests have to meet a series of requirements: have personnel trained in molecular biology techniques; have the capacity to work with level 2 infectious samples, biosafety cabinet and adequate equipment; have the capacity to produce inactivation reagents, and manage extraction techniques by their own means that do not subtract capacities from hospital centers, among others

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Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model

Researchers of NANBIOSIS Units at JUMISC. led by Verónica Crisóstomo, Scientific Director of NANBIOSIS unit 24 of Medical Imaging, have just published an article in the Journal Scientific Report

Cardiovascular diseases, especially ischemic heart disease, are the leading cause of mortality worldwide. Conventional treatments have contributed to reduce early mortality after an acute myocardial infarction, but do not recover the damaged myocardial tissue. In the last two decades stem cell therapy has been studied for that purpose. Nowadays it is known now that stem cells are able to secrete combinations of biomolecules that modulate the composition of the damaged cardiac environment contributing to functional tissue repair by stimulating the migration, proliferation and survival of endogenous cardiac progenitor cells as well as attenuating fibrosis and modulating inflammation. Among the secreted substances, there are different cytokines, extracellular vesicles and growth factors including insulin-like growth factor-1 (IGF-1). Our researchers’ goal in this work has been to assess the safety and effectiveness of an intracoronary infusion of microencapsulated IGF-1 after acute myocardial infarction in a clinically relevant swine model of reperfused myocardial infarction.

Large animal studies have been conducted by the ICTS “NANBIOSIS”, more specifically by Units 14, 21, 22 and 24 of the Jesús Usón Minimally Invasive Surgery Centre.

Article:

Báez-Díaz, C., Blanco-Blázquez, V., Sánchez-Margallo, F. et al. Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model. Sci Rep 10, 7166 (2020).

https://doi.org/10.1038/s41598-020-64097-y

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JUMISC will invest 7.3 million in the development of new surgical robots

The Jesús Usón Minimally Invasive Surgery Center (CCMIJU), partner of NANBIOSIS, has been granted the with the FID-CPI Innovative Public Procurement Program of the Ministry of Science and Innovation, as well as with the support of the Ministry of Economy, Science and Digital Agenda of the Board, for the development of the TREMIRS project “Minimally invasive robotic surgery systems” aimed at improve current techniques in laparoscopy and microsurgery

TREMIRS will improve current robotic surgical systems, providing better service to the patient, better ergonomics to the surgeon and greater benefits to the surgical team, achieving an increase in the quality of care. The project is endowed with 7,345,300 euros, and is co-financed 80 percent by the European Regional Development Fund-FEDER.

During the three-year duration of the project, a robotic platform for laparoscopic surgery will be developed that will facilitate new surgical approaches, improvements in the ergonomics of surgeons, advances in vision systems for the entire surgical team and the availability of new portable training tools. .

In the field of microsurgery, TREMIRS will develop a teleoperated robotic platform for reconstructive microsurgery, consisting of robotic microinstruments with high maneuverability and precision, the Board reports in a press release.

It will be used for soft tissue manipulation to perform microsurgical techniques such as anastomosis, suturing, and ligation of small anatomical structures such as blood vessels, nerves, and lymphatic ducts.

The development of both platforms will mean making new equipment available to the National Health System and the Extremadura Health System that is currently not available in the market and that will allow for the improvement of the quality of the services provided to the patient and improvements in surgical results.

Source: https://www.hoy.es/caceres/centro-cirugia-minima-20200419121007-nt.html#vca=fixed-btn&vso=rrss&vmc=tw&vli=C%C3%A1ceres

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Course on Coloretal Endoscopy for Surgeons

JUMISC and the Spanish Association of Coloproctocology has organised the ICourse on Coloretal Endoscopy for Surgeons which wil take place at JUMISC on March, 9 -10, co-Directed by  Fernando de la Portilla de Juan (President of Spanish Association of Coloproctology) and Francisco M. Sanchez Margallo (Deputy Scientific Director of NANBIOSIS)  

The course includes colonoscopy practices in pig and canine models.

For further information and inscriptions: here

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Preliminary Market Consultation (CPM): technology development in the field of organ preservation.

The Center for Industrial Technological Development (CDTI) has selected the proposal presented by JUMISC, partner of NANBIOSIS, on the technological challenge of an alternative cold preservation system in a preliminary market consultation.
On February 4, the Technical Conference of the Preliminary Market Consultation of the Organ Preservation Challenge was held.
The objective of the Preliminary Market Consultation was to obtain information from the market operators in the Organ Preservation technologies in order to adequately define the future potential for pre-commercial Public procurement and adequately inform the economic operators of the requirements that will be required in the Potential future tender for pre-commercial public purchase.
The Conference was directed by Ms. Ana Isabel Rodríguez Belda, Innovative Public Procurement Technician of the CDTI and Mr. Franciso M Sánchez Margallo, Scientific Director of JUMISC and Deputy Director of NANBIOSIS who, after reviewing the background and problems related to the preservation of organs for transplantation, he presented the technological challenge presented by JUMISC and selected by the CDTI and how its preclinical animal validation in JUMISC can be of great help in human ogan transplants
The conference included a visit to the facilities of CCMIJU, partner of NANBIOSIS ICTS

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VII Course of Microscopic and Piezoelectric Techniques in Dentistry: Endodontics, Implantology and Prosthetics

CCMIJU has organised the VII Course of Microscopic and Piezoelectric Techniques in Dentistry: Endodontics, Implantology and Prosthetics, which wil take place at JUMISC from March 3 till June 27 2020 under the Direction of Alberto Anta Escudero. (Profesor of the UPV-EHU), Gorka Santamaría Arrieta (Professor of the UPV-EHU), Jon Eskurza Pérez (Endodontics Specialist. Private Clinic) and Francisco Miguel Sánchez Margallo (Deputy Scientific Director of NANBIOSIS)

The general objective of the course is the knowledge of the enodontology magnification, necessary materials and instruments and related ergonomic aspects. Training in magnification in dentistry

Frurther information: Programm and inscriptions

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EUROAGE: to improve people’s quality of life and increase healthy life expectancy

The Center for Minimally Invasive Surgery (JUMISC), partner of NANBIOSIS, as the main beneficiary of the Spain-Portugal EUROAGE cross-border cooperation project that promotes active aging in the region, has presented its results and its impact on society, within the Spanish-speaking meeting ‘ Forum of Iberian Stories. 30 years of the INTERREG Spain-Portugal Cross-Border Cooperation Program (POCTEP) ’.

Specifically, the event has been organized by the agencies EFE and LUSA, and took place this past Wednesday at the headquarters of the Spanish agency in Madrid, with the support of the Directorate General for Regional Policy (DGRegio) of the European Commission.

Its objective has been to address the main achievements of the program and the new challenges demanded by the future of both territories. EUROAGE, belonging to the Cooperation Area 4 (Extremadura-Centro-Alentejo), is focused on promoting healthy autonomous life, mainly for the elderly, but also for dependent people, through the promotion of innovative initiatives based on technologies and knowledge developed by the R&D agents.

In turn, the European project promotes active aging through physical, cognitive and socio-emotional activity, with the main objective of improving people’s quality of life and increasing healthy life expectancy, at the same time that will affect the reduction of expenses, in the optimization of resources in public health systems and in the modernization of the business fabric of the sector.

Although the main beneficiary of the European project is the Jesús Usón Minimally Invasive Surgery Center, other institutions also participate, such as the Castelo Branco Polytechnic Institute, the University of Coimbra, the Extremadura Social Cluster, the University of Extremadura and the Polytechnic Institute Give Guardian

EUROAGE includes the development of materials for health literacy, applications for the improvement of physical and cognitive well-being and an integrated system for the promotion of active aging, as well as different social and welfare robots.

Source of information: Región Digital

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New book by NANBIOSIS U14: Basic research procedures in the cell therapy laboratory

Researchers of NANIOSIS Unit 14 at JUMISC have published a new book titled Basic research procedures in the cell therapy laboratory, in which some basic techniques and general principles for adult stem cell research are explained.

Stem cells are cells capable of differentiating into a wide variety of cell types and can be isolated from different tissues such as. They have regenerative and anti-inflammatory properties thanks to the secretion of paracrine factors. Currently, these cells are being widely used in clinical trials for the treatment of different diseases such as Crohn disease, multiple sclerosis, diabetes, rheumatoid arthritis or myocardial infarction.
In this book, some basic techniques and general principles for working in a research laboratory in Cellular Therapy are explained in a simplified manner. In the same way, a series of basic knowledge are exposed that must be taken into account for the correct handling of the cells and their environment.
This book is not intended to be a detailed manual of laboratory procedures or a book on cell management for clinical use, but its purpose is to describe part of the protocols developed by the Cell Therapy Unit of NANBIOSIS at the Jesús Usón Minimally Invasive Surgery Center and which have the objective of evaluating the effectiveness and safety of these cells in the preclinical setting.

Book: Basic research procedures in the cell therapy laboratory. Álvarez Pérez, Verónica, García Casado, Javier, Sánchez-Margallo, Francisco.
ISBN 13: 978-84-17959-64-7

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PICCOLO Project 7th Face-to-Face Meeting at JUMISC (NANBIOSIS)

The Piccolo consortium members met at JUMISC (Cácere) last on 21st-22nd January to hold the 7th face-to-face meeting.

Project partners had the chance to visit Nanbiosis U21 Experimental operating rooms led by Francisco M. Sánchez Margallo and participate in a training session with the prototype demo. A murine specimen was analysed ex-vivo with the probe and the clinicians had the opportunity to evaluate the features present in a neoplastic polyp.

The meeting agenda included a general overview of the project, the status update of OCT (Optical Coherence Tomography), MPT (Multiphoton Tomography) and fluorescence technologies, deep learning algorithms preliminary results, the final steps to follow with the validation on animal and human samples and the exploitation and dissemination plan. All members agreed to focus on the preparation of dissemination material with the results of the project, such as a brochure or videos to approach the project to the scientific community.

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