+34 679 490 537info@nanbiosis.com

Posts Taged biomedical-devices-for-applications-in-regenerative-medicine

From natural by-products to cell delivery systems for regenerative medicine

Researchers from NANBIOSIS U10 Drug Formulation unit (CIBERBBN – UPV/EHU led Rosa María Hernández, have developed a biomedical device consisting of by-products from the food industry and which displays excellent properties for use in regenerative medicine. The work has been published in the Green Chemistry Jurnal, one of the most prestigious international journals in chemistry and the second most important one in the field of sustainable science. The work has also been selected for the cover page of this issue.

Researchers in the UPV/EHU’s NanoBioCel and Biomat groups have developed a biomedical device consisting of by-products from the food industry and which displays excellent properties for use in regenerative medicine. The novel device comprises soy protein and chitin, which form a matrix with a porous, interconnected microarchitecture similar to that of certain body tissues.

Added to the growing need in recent years to develop new therapies for biomedical applications is the widely called-for social requirement to be environmentally friendly. In this respect, the group of researchers has shown that natural by-products from the food industry, normally discarded in industrial processes, could be an excellent source of biomaterials for producing biomedical devices.

“It is important to point out that to date no one has exploited the potential in regenerative medicine displayed by soy protein and chitin blended in a microporous matrix,” stressed the researchers. “As the first milestone in this respect, this novel device incorporates two natural components obtained from the food industry, thus contributing towards the widely called-for social requirement to upgrade waste from production on an industrial level. The device has also displayed some physico-chemical and mechanical properties suitable for applications in regenerative medicine. What is more, it has also been found to be totally biocompatible not only in in vitro cell lines but also in an in vivo murine model.  Finally, we have confirmed that this device is capable of hosting a large number of viable stem cells inside it, thus increasing its level of bioactive compound secretion and displaying its potential as a very effective vehicle in cell therapy.”

This biotechnological approach may have a potentially successful application in the matrix-based regenerative medicine industry. These devices capable of hosting stem cells are destined to be the revolution, not only in biomedical research but also in everyday clinical practice. “Clinical scenarios as complex as chronic injuries or bone problems need a multifocal approach which combines bioactive matrices with biological agents having regenerative effects,” they concluded.

Article of reference

Read More

NANBIOSIS organizes a forum for researchers and companies. Dates (probably February 2018) and location (probably Madrid) will be announced soon.

NANBIOSIS organizes a forum for researchers and companies. Dates (probably February 2018) and location (probably Madrid) will be announced soon.

The theme of the Forum is INTELLIGENT BIOMATERIALS / FUNCTIONALIZATION AND BIOMEDICAL DEVICES FOR APPLICATIONS IN REGENERATIVE MEDICINE AND DRUG DELIVERY.

The forum is presented through 2 sessions:

• First session: Short interventions of the latest advances and developments in the lines of research developed by the groups and platforms of Nanbiosis and description of the needs and demands of industry in that area. The companies and groups that request it will be able to have about 10 ‘to present their lines of research and / or needs and demands in relation to the thematic of the forum.
• Second session: Bilateral company-group / platform meetings to identify possible collaborations. These meetings will be pre-scheduled on request.

If you are interested in participating, contact Eduard Farré (628.943.198, efarre@arvor-ing.com) or with Jesús Izco (679.490.537, jmizco@ciber-bbn.es).

 

Read More