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NANBIOSIS renews its accreditation as Singular Scientific and Technical Infrastructure (ICTS)

The Minister of Science and Innovation, Diana Morant, chaired the XI meeting of the Council for Scientific, Technological and Innovation Policy, in which the update of the Map of Singular Scientific and Technical Infrastructures, the ICTS Map for 2021-2024, was approved.

The ICTS are facilities dedicated to cutting-edge research of the highest quality, as well as to the transmission, exchange and preservation of knowledge, technology transfer and the promotion of innovation.

The map has 29 ICTS distributed among all the territories, includes NANBIOSIS, the Infraestructure for Production and Characterization of Nanomaterials, Biomaterials and Systems in Nanomedicine with its 26 units.

As a novelty, the update incorporates four new nodes or infrastructures associated with the ICTS. Specifically, the NASERTIC computing node in Navarra, the CIEMAT computing node in Extremadura and Madrid, and the Port d’Informació Científica data node in Catalonia are incorporated into the ICTS Red Española de Supercomputación, while the Center for Microanalysis of Materials is associated as a node to the new distributed Infrastructure of Applications Based on Accelerators. Likewise, Navarra incorporates an infrastructure to this map for the first time, an instrument that improves the management of ICTS and helps these organizations to access funding from the Ministry as well as regional and European funds, particularly the ERDF funds and the Recovery Funds and Resilience (MRR).

In this sense, the minister announced that the next call to strengthen the ICTS, scheduled for the first half of 2022, will allocate 38 million euros until 2025 to finance lines of investment associated with the construction, development, instrumentation, equipment and improvement of its scientific- techniques. The previous call, published in 2021, dedicated nearly 37 million euros to these infrastructures.

NANBIOSIS is one of the five ICTS in the area of health sciences and biotechnology. This thematic area has significantly increased its representation in the current ICTS Map. Under the concept of distributed ICTS, infrastructure networks have been established in the field of imaging, nanotechnology and omics sciences. In addition, the high biological safety laboratories are also reinforced, expanding the infrastructures of this type that offer their services.

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1,800,000 euro for the improvement of NANBIOSIS laboratories

The final decision on the call for funding of Singular Scientific and Technical Infrastructures (ICTS) within the framework of the Recovery, Transformation and Resilience Plan in 2021 for has been published. These grants are intended to facilitate the execution of the Strategic Plans of the ICTSs included in the current National Map of ICTSs, through the execution of the investments provided for in their investment plans and declared of high priority by the Advisory Committee for Singular Infrastructures (CAIS).

Two applications were submitted to this call by NANBIOSIS: one by the CIBER node named “Towards a new generation of Infrastructure for the design, production and preclinical characterization of nanomedicines, biomaterials and biomedical systems in the units of the CIBER node of NANBIOSIS ” for the amount of € 2,522,128.02 of which € 1,785,706.36 have been granted, and another for the BIONAND node entitled “Update and improvement of the equipment of the BIONAND node of the NANBIOSIS distributed ICTS ”, for the amount of € 339,633.59, of which € 29,000 have been awarded.

These grants will allow the acquisition and improvement of the equipment and laboratories for the preclinical production and characterization of biomaterial nanomedicines and NANBIOSIS biomedical systems.

This call from the Ministry of Science and Innovation is funded with 37 million euros by the Recovery and Resilience Mechanism of the European Union. This is the first grant of aid for all ICTS in the last decade that is approved with funds from the General State Budget that finances 100% of the eligible costs and will allow the development and improvement of critical facilities for science and Spanish innovation. The Ministry of Science and Innovation has announced that in 2022 another call for 37 million euros will be published to finance actions of the new strategic plans of the ICTS 2021-2024.

The reinforcement of NANBIOSIS research capacities through these projects will result in a qualification of the research tissue at the national level necessary for the development of the next generation of advanced therapy drugs and diagnostic innovation linked to precision medicine and ensure the production of essential drugs.

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NANBIOSIS in the new poster of ICTS map published by Spanish Goverment.

ICTS underpins the Spanish reputation for research excellence.

In the picture: the new poster of the ICTS map in which NANBIOSIS facilities have been highlighed with a red square

The term Unique Scientific and Technical Infrastructure (ICTS) refers to facilities, resources, or services for the development of top-quality cutting-edge research, as well as the communication, exchange, and preservation of knowledge, the transfer of technology, and promotion of innovation. They are unique or exceptional in their fields, with a high cost of investment, maintenance, and operation, and are of a strategic importance that justifies their availability to all actors in the field of R&D&I. The ICTS share three fundamental characteristics; they are infrastructures with public ownership, unique and open to competitive access.

ICTS offer an opening capacity percentage of their essential services under ‘Competitive Open Access’ for the use by national and international public and private sector researchers, with the support of technical and administrative personnel of the ICTS. Infrastructures access is ruled by a public “Access Protocol” that describes the procedure and criteria for access to the infrastructure. The main features of ‘Competitive Open Access’ are that R + D + i quality of activities developed at the infrastructure should be proven and that requests for access should be prioritized on the basis of objective criteria.

The dissemination of ICTS and their capabilities is essential to provide Spanish and international researchers with access to a large base of quality services and facilities, a basic requirement for the development of excellent science.

The new posster pushised by the General Subdirectorate of Large
Scientific-Technical Facilities of the of the Sapanish Ministry of Science and Research Innovation helps to disseminate and understand the map of ICTS wich are located throughout the country

NANBIOSIS, is one of the five ICTS in the field of Health Sciences and Biotechnology

Further informations: MICINN

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We are pleased to inform that the new book of Unique Scientific and Technical Infrastructures (ICTS) has been published by the Spanish Ministery of Innovation, Science and Universities with the collaborations of the ICTS.

The Spanish Map of Unique Scientific and Technical Infrastructures (ICTS), goups biomedical technologies, cleanrooms, supercomputers, advanced lasers, telescopes, underground laboratories, synchrotrons, particle accelerators, biological reserves, solar, oceanic and hydraulic platforms, oceanographic research ships, and polar bases in Antarctica. A total of 29 ICTS, made up of 62 nodes, allow for ambitious research projects that attract first-rate talent and enhance the technological and innovative industry capacities.

“Through a one-stop system, NANBIOSIS provides comprehensive solutions that are tailored to the challenges thaat researchers face in biomedicine… its configuration means pioneering multidisciplinary studies can be conducted. Some examples are outlined below.”


Among these examples, several results combining the expertise of several Units of NANBIOSIS: an original method to prepare smaller nanoparticles of polylactic-co-glycolic acid (PLGA) functionalised with cell-penetrating peptides (CPP), which penetrate the cell membrane and release controlled drug doses into the cells; an innovative medication administration system based on emerging bionanotechnology with protein nanoparticles that selectively deliver lead the therapeutic agent to the tumour cells or a bioactive surgical mesh, covered with adult stem cells, to reduce the inflammatory process associated with implanting this type of material that proved a beneficial effect on the biocompatibility in animal models.

As Pedro Duque, Spanish Minister of Innovation, Science and Universities says in its prelude “The Unique Scientific and Technical Infrastructures described in this book are crucial for Spain and its science, technology, and innovation. I encourage you to browse the pages of this book and discover the state-of-the-art infrastructures that represent the scientific and technological capacity that exists in Spain today. You won’t regret it

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The European Union highlights the relevance of the JUMISC’s Cutting-Edge Infraestructures and Technology, recognized as ICTS.

Jesús Usón Minimally Invasive Surgery Center (JUMISC), from Cáceres, partnert of NANBIOSIS, has recently made headlines on the website of the European Commission as an innovative center for Biomedical and Health Research.

In the interview to his Director, Francisco Miguel Sanchez Margallo, he explained how European Funds allowed Infraestructures and Vanguard Technology for biomedical research at the CCMIJU, which have already been recognized, as part of NANBIOSIS, with CIBER-BBN and BIONAND, as “Singular Scientific and Technical Infrastructure” (ICTS).

Complete news at European Commision’s Website: https://ec.europa.eu/spain/news/investeu_caceres_es

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NANBIOSIS participated in the Big Science Business Forum 2018 in Copenhagen

During the days 26-28 of February took place in Copenhagen, Denmark the Big Science Business Forum 2018 in which NANBIOSIS was present.

Big Science is the term that is used to designate research efforts of great magnitude, due to its high cost, complexity and scientific importance. Scientific progress is increasingly based on large-scale projects, with increasingly global scientific projects and increasingly collaborative research.

The Big Science Business Forum 2018 brought together more than 650 delegates from 25 countries, and representatives of more than 250 companies, being an important event to know business opportunities in the coming years as well as to establish Networks, with more than 1000 central players and 800 individual 1-1 business meetings.

In the photo, together with representatives from CDTI, Jesús Izco, Coordinator of  NANBIOSIS a Large Scale Facility (ICTS), and Manuel Lozano, Director of CNM-CSIC, which houses another ICTS: the “Integrated Micro and Nanofabrication Clean Room”,

The Integrated Clean Room for Micro and Nano fabrication (SBCNM) is a Large Scale Facility (ICTS) dedicated to the development and application of innovative technologies in the field of Microelectronics together with other emerging Micro/Nanotechnologies. It is embedded administratively in the Centro Nacional de Microelectrónica – Instituto de Microelectrónica de Barcelona – (IMB-CNM), a research centre belonging to the Spanish Council of Scientific Research (CSIC). It is an open access facility that aims at helping national and international research groups to carry out R&D activities thanks to the availability of a set of complete micro and nanotechnologies and processes housed in a highly specialised Clean Room environment devoted to R&D&i of excellence, and driven by an expert team. Such support ranges from technology awareness to the development of basic demonstrators, or small series of prototypes.

NANBIOSIS is a distributed ICTS for the design and production of biomaterials, nanomaterials and devices to their preclinical validation, integrated by the Center for Biomedical Research of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) and the Center for Minimally Invasive Surgery Jesus Usón (CCMIJU ). NANBIOSIS consists of 27 units coordinated under a single window model. Together, these units offer a complementary service that includes the design, production of biomaterials and nanomaterials and the characterization of these bio and nanomaterials, tissues, devices and medical systems from a point of view, physical-chemical, functional, toxicological and biological (including preclinical validation), focused on biomedical applications, which allows for the development of a therapeutic agent until it reaches preclinical validation under the coordination of some of the best Spanish research groups in bioengineering, biomaterials and nanomedicine.

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NANBIOSIS at the CIBER-BBN X Annual Conference and 1st meeting of the NANBIOSIS SAB

The X Annual Conference of CIBER-BBN, held in Sevilla last 28 and 29 of November, dedicated a Session to NANBIOSIS on Monday afternoon, to which attended national and international representatives of industry and academia users of NANBIOSIS, representatives of EATRIS and members of the Scientific and Technical Advisory Committee of NANBIOSIS, as well as the CIBER-BBN and the CCMIJU researchers.

Jaume Veciana, Scientific of NANBIOSIS and Ángela Fernández Curto, Assistant Deputy Director General for Planning of Scientific and Technological Infrastructures of Spanish Goverment presented the Unique Technical Scientific Infrastructure (ICTS) of CIBER-BBN and JUMISC for the production and characterization of biomaterials, nanomaterials and devices until their preclinical validation. Among the biomedical applications that frame the activity of NANBIOSIS are diagnostic, regenerative medicine and drug administration, as well as its next Cascade Characterization Service for the preclinical evaluation of nanomedicines.

The project “PRONANBIOSIS” funded by the Spanish Ministry of Economy and Competitiveness with a “Network of Excellence” to consolidate the unified management model of NANBIOSIS, to boost its internationalization and strategic positioning as well as to promote a complete nanomaterials characterization cascade service, was also presented and some of the” success stories “of the ICTS where explained.

Since its launch in July 2015, NANBIOSIS has received more than 250 access requests, with an average participation of about 50 competitive projects per year and annual revenues for its services of between 1 and 2 million euros. Among its users, there are more than 100 companies, especially pharmaceutical laboratories, and more than 300 research groups. In addition, its 27 units are involved in several national and European projects, such as BERENICE (nanoformulation of the active to combat Chagas disease), DRIVE (development of a device with pancreatic cells for diabetes treatment) and several public- Former INNPACTO (PHYTEC -Development of bioactive coated medical products for bone regeneration- and VITILIGO -Development of a new advanced therapy drug for the treatment of Vitiligo-), several projects Challenges Collaboration, or the Network of Excellence Pronanbiosis for the promotion and Consolidation of the ICTS, among others.

At the Conference, the NANBIOSIS Scientific Advisory Committee convened to discuss the key actions of its next Strategic Plan, such as the new Cascade Characterization Service for the preclinical evaluation of nanomedicines.

NANBIOSIS at the CIBER-BBN X Annual Conference and 1st meeting of the NANBIOSIS SAB
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X Annual Conference of CIBER-BBN

The next days 28 and 29 of November the X Annual Conference of CIBER-BBN will be held in Seville.

Within this Conference, 3 thematic forums have been organized for clinical translation, where doctors will present the current challenges of diagnosis and treatment in certain diseases and a debate will open between doctors and
researchers to develop research lines and projects aimed at solving those needs.

Taking advantage of the presence of clinical professionals, NANBIOSIS has organized a session dedicated to presenting itself as “Unique technological scientific infrastructure” (ICTS in Spanish) as well as the nodes that are
part of it. Some cases of success and results will be also presented in order to ´make known the services and advantages offered by NANBIOSIS and facilitate the translation of the research developed in the ICTS.

This session will be attended by Ángela Fernández Curto, Assistant Deputy Director General for Planning of Scientific and Technological Infrastructures MINECO who will explain what is and “ICTS”, Jaume Veciana and Jesús Izco, Scientific Director and Coordinator of NANBIOSIS respectively who shall give some general explanations about NANBIOSIS and what has been done in this year of progress since its recognition as ICTS by MINECO,

Finally, The broader part of the session will be led by the following Coordinators or Scientific Directors of the NANBIOSIS Platforms, who will make a brief presentation of each and will present some cases of success:

Also at the Conference, the NANBIOSIS Scientific Advisory Committee will meet to discuss the key actions of its next Strategic Plan, such as the new Cascade Characterization Service for the preclinical evaluation of nanomedicines.

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Nanbiosis new ICTS incorporation

The new map of Scientific and Technological Infrastructures (ICTS), was updated by the Council for Science Policy, Technology and Innovation last 7th of October, 2014, which  incorporated The Integrated Infrastructure on Production and Characterization of Nanomaterials, Biomaterials and Systems in Biomedicine (NANBIOSIS) . The new ICTS is integrated by the CIBER-BBN and the Center for Minimally Invasive Surgery Jesus Uson (JUMISC).

Pablo Laguna, scientific director of the CIBER-BBN noted that “this recognition is the result of efforts of both institutions to try to provide research services of high quality and added value, usually high-cost equipment, which is available to the scientific community, giving them greater and better use and avoiding costly and not always necessary redundancies. Furthermore, the fact that these infrastructures are coordinated by experts in their subjects, makes the scope of these infrastructures to exceed the national territory to become an actor at international level “.

The research infrastructure is aimed at medical applications and tries to provide a complete service and easy access through a “single contact point”, which includes the design, production of biomaterials and nanomaterials characterization of these materials, tissues , medical and systems from a physical, chemical, functional, toxicological and biological point of view including preclinical validation.

NANBIOSIS’ Units are located in Zaragoza, Badajoz, Barcelona, ​​Caceres, Madrid, Valencia and Álava. Provides personnel and cross-cutting equipment in all the units in which infrastructure is organized, with dedication to service to the entire scientific community.

The new Spanish map of ICTS has 29 infrastructures and has been updated taking into account criteria of highest scientific quality, technology and innovation, subjecting candidates to a rigorous process of independent evaluation.n (check ICTS map)

The so-called singular scientific and technical infrastructures (ICTS) are large installations, resources, facilities and services, unique in its kind, that are dedicated to cutting edge and high quality research and technological development, as well as to promote exchange, transmission and preservation of knowledge, technology transfer and innovation. Its main objective is provision to national and international scientific, technological and industrial community of essential scientific and technical infrastructure for the development of a scientific and technological research unique or exceptional in its genre, with a very high cost of investment and maintenance and whose importance and strategic nature justifies their availability for the whole R + D + i collective. Therefore, the ICTS are infrastructures of PUBLIC  ownership, are UNIQUE and OPEN to competitive access to users of the whole research community in the public and private sector..

Logo ICTS Nanbiosis
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