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Nanbiosis

U18-E09. Tissue Arrayer

Tissue Arrayer for processing multiple samples in a single slide for immunohistochemistry staining

 

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U13-E3. Atomic Force Microscopy

AFM: Atomic Force Microscopy JPK. AFMs can be used to measure the forces between the probe and the sample as a function of their mutual separation. This can be applied to perform force spectroscopy.

 

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U12-E21. Fluorimeter Cary Eclipse (Varian)

U12-E21. Fluorimeter Cary Eclipse (Varian)

Fluorimeter Cary Eclipse (Varian) for fluorescence, phosphorescence, chemiluminiscence, bioluminiscence measurements.

U12-E21. Fluorimeter Cary Eclipse (Varian)
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U12-E20. Osmometer Type 15 (Löser Messtechnik)

U12-E20. Osmometer Type 15 (Löser Messtechnik)

Description:

Instrument for the determination of osmolality via the measurement of freezing point

Applications:

Measurement of osmolality of biomedical samples

U12-E20. Osmometer Type 15 (Löser Messtechnik)
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U12-E19. HPLC 1525 Series (Waters)

U12-E19. HPLC 1525 Series (Waters)

Description:
Waters 1500 series Chromatograph equipped with a binary gradient pump (maximum flux = 10 mL/min and maximum pressure of 6000 psi or 414 bar), UV detector model 2489 (wavelength 190-600 nm), refractometer model Waters 2410 (flux = 0.03 to 10 mL /min and internal temperature control from 30 to 50˚C) and injector model Waters 2707 (injection volume = 0-50µL).

Applications:
High Pressure Liquid Chromatography (HPLC) is an analysis technique that allows the separation of nonvolatile compounds from a mixture, such as inorganic compounds, aminoacids, peptides, proteins, lipids, sugars, drugs, petroleum derived products, synthetic polymers, etc. Qualitative and quantitative analysis are possible with HLPC.

U12-E19. HPLC 1525 Series (Waters)
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U12-E18. Viscosimeter RVDV-II+P (Brookfield)

U12-E18. Viscosimeter RVDV-II P (Brookfield)

Description:
Brookfield viscometer with a wide measurement range from 25 mPa.s to 64 MmPa.s. It is equipped with an accessory (Small Sample Adaptor SSA) for samples of small volume (7-13.5 mL).

Applications:
Viscosity measurements.

U12-E18. Viscosimeter RVDV-II P (Brookfield)
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U12-E17. Zetasizer NanoZ (Malvern Instruments)

U12-E17. Zetasizer NanoZ (Malvern Instruments)

Description:
Instrument for the measurement of zeta potential, using the M3-PALS technology for the determination of electrophoretic mobility.  Temperature can be controled from 2 to 90 ˚C. It uses disposable capillary cells “Universal Dip Cell” for standard Zeta potential measurements in organic and aqueous solvents, and it can use the “High Concentration Cell“ for measurements at high concentrations

Applications:
Measurement of electrophoretic mobility and zeta potential in dispersions

U12-E17. Zetasizer NanoZ (Malvern Instruments)
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U12-E16. Autosorb IQ (Quantachrome Instruments)

U12-E16. Autosorb IQ (Quantachrome Instruments)

Description:
The Quantachrome Autosorb iQ-AG equipment determines gas adsorption/desorption curves, for the calculation of specific surface area and pore size analysis. This equipment allows the simultaneous degassing of two samples and the physisorption analysis of a third sample, at relative pressures above P/P0 > 1×10-3. The gas sorption analyzer is equipped with a cryogenic dewar for measurements until 90 hours.

Applications:
Characterization of the porosity and surface area of nanoparticles, macroporous, macro/mesoporous and mesoporous materials like aluminas, silicas and other materials including M41S materials (eg. MCM-41), PMOs, KITs and many SBAs.

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U12-E16. Autosorb IQ (Quantachrome Instruments)
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U12-E15. SEM Hitachi TM-1000 (Hitachi)

U12-E15. SEM Hitachi TM-1000 (Hitachi)

Description:
Tabletop Scanning Electron Microscope.

Applications:
Observations of the morphology of solid samples, such as polymeric and synthetic particles, meso/macroporous materials, textiles, etc., with high field depth (it allows focusing simultaneously on a wide portion of the sample) and relatively high resolution (in the nanometer range). Samples do not need to be electrical conductive, and therefore, coating with a very thin metal layer (e.g. Au, Pd) is not always required. The only sample requirement is the absence of volatile components, including water humidity

U12-E15. SEM Hitachi TM-1000 (Hitachi)
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U10-E38 Equipment of biopharmaceutical characterization of pulmonary formulations with Breath Simulator and Alberta Idealised Throat (AIT)

Equipment of biopharmaceutical characterization of pulmonary formulations with Breath Simulator and Alberta Idealised Throat (AIT)

 

1) NGI Cascade Impactor: It’s an analytical tool for the development of inhalation products. It’s use for the testing of all inhalation formulations and devices: MDIs, DPIs, nebulizers and aerosol and nasal sprays. It’s the new “workhorse” of the pharmaceutical industry.

2) Alberta Idealised Throat (AIT): before entering the lungs, aerosols must traverse the mouth-throat. So it’s important to be able to mimic aerosol deposition and flow in the human mouth-throat when studying inhaled aerosols. The Alberta geometry has been shown to do a remarkable job of mimicking the aerosol and flow motion in the human mouth-throat and allow researchers examining  and testing aerosols inhaled orally.

3) Breath Simulator: are increasingly used in testing orally inhaled and nasal drug products (OINDPs) to replace existing constant flow conditions with breathing profiles more representative of conditions in vivo. It can be used for improved IVIVC applications, with real breath profiles generated in clinic.

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