U29-S02. Modification of oligonucleotides. (Remote) OUTSTANDING
Modification of oligonucleotides during and post synthesis to meet user requirements:
+34 9340006100 -ext. 437807-info@nanbiosis.com
Modification of oligonucleotides during and post synthesis to meet user requirements:
Special nucleotides for oligonucleotide synthesis For those services identified as outstanding, at least 20% of their capacity is open under competitive access. See Annex 1 of ACCESS PROTOCOL (provided by Nanbiosis) for details on % of openness for each service
UV-Visible and luminometer Reader used in luciferase and MTT assays
Electrophoresis apparatus with several vertical and horizontal cuvettes for agarose and polyacrylamide (PAGE) gel electrophoresis.
Automatic synthesizer which can be operated at a range of scales (40, 200, 1000 nanomols). A large variety of monomers can be incorporated using the phosphoramidite methodology such as natural and modified DNA, RNA monomers as well as fluorophores and other modifications.
Analytical and preparative high-performance liquid chromatography (HPLC) system with a diode array detector.
Speed-Vac evaporators for removal of water in oligonucleotide samples
UV-Visible spectrophotometer equipped with a Peltier temperature gradient to run thermal denaturation assays followed by UV absorption.
Spectrofluorimeter equipped with a Peltier temperature gradient to run thermal denaturation assays and characterization of DNA-binding drugs followed by fluorescence.
Synthesis of oligonucleotides at various different scales (100 microg to 5 mg) and purification using HPLC and/or desalting.