NANBIOSIS U6 contributed to BIOMED 2025 at ICMAB with a talk on ITC and SPR, showcasing advanced tools for biomolecular interaction analysis.
Barcelona, October 2025 — last 22 October 2025, the Institute of Materials Science of Barcelona (ICMAB–CSIC) hosted the BIOMED 2025: Workshop on Experimental Techniques for Biomedicine, bringing together early-career researchers to explore pivotal biomedical characterization methods.
As a key contributor, NANBIOSIS Unit 6, the Soft Materials Service at ICMAB-CSIC, showcased its expertise through a technical talk delivered by David Piña Muñoz — “Unraveling and Quantifying Molecular Biointeractions through ITC and SPR.” This presentation underscored the Unit’s advanced instrumentation capabilities in isothermal titration calorimetry (ITC) and surface plasmon resonance (SPR).
Unpacking ITC and SPR capabilities
During his talk, David Piña explained how ITC provides thermodynamic profiles of molecular interactions by directly measuring heat changes upon binding, offering insights into binding affinity, stoichiometry, enthalpy, and entropy. Meanwhile, SPR enables real-time, label-free monitoring of biomolecular binding kinetics — capturing association and dissociation rates with high sensitivity. Together, these complementary techniques empower researchers to comprehensively characterize biomolecular interactions.
These services are part of the broader Soft Materials platform at Unit 6, which integrates a suite of advanced characterization tools tailored for soft and biomaterials research.
About NANBIOSIS Unit 6: Soft Materials Service
NANBIOSIS Unit 6 is based at ICMAB–CSIC in Barcelona, coordinated by Prof. Nora Ventosa, who also leads the NANOMOL group. The Unit specializes in the development, processing, and characterization of nano- and microstructured molecular soft materials with therapeutic or biomedical relevance.
A standout capability of Unit 6 is its compressed-fluid biomaterials processing platform, including the proprietary DELOS-SUSP one-step method using compressed CO₂. This technology enables the scalable production of particulate biomaterials with controlled size, internal structure, and supramolecular organization — from milliliters to liters. The Unit is also ISO 9001 certified, ensuring high-quality standards across its operations.
Impact of the BIOMED 2025 Workshop
The BIOMED 2025 workshop was designed to support early-stage biomedical researchers, offering a hybrid format (in-person and online) that covered a spectrum of techniques — from cell culture basics to advanced biophysical analysis. By delivering a session on ITC and SPR, NANBIOSIS Unit 6 not only contributed scientific knowledge but also reinforced its role as a core technology provider for the biomedical community.
Participants benefited from expert-led discussions, hands-on insights into characterization tools, and networking opportunities with leading researchers in materials science and biomedicine.
Further Information & Contacts
- Soft Materials Service, ICMAB-CSIC: Visit the SOFT ICMAB website for more details on instrumentation and services.
- NANBIOSIS Unit 6: Learn about U6 – Soft Materials Service, its research lines, and technological capabilities.
- Contact: You can reach the SOFT Materials Service at ICMAB via servicios.soft@icmab.es.
What is NANBIOSIS?
The goal of NANBIOSIS is to provide comprehensive and integrated advanced solutions for companies and research institutions in biomedical applications. All of this is done through a single-entry point, involving the design and production of biomaterials, nanomaterials, and their nanoconjugates. This includes their characterization from physical-chemical, functional, toxicological, and biological perspectives (preclinical validation).
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NANBIOSIS has worked with pharmaceutical companies of all sizes in the areas of drug delivery, biomaterials and regenerative medicine. Here are a few of them:
