U2. Custom Antibody Service Unit (CAbS)
The facility is located in the Institute of Advanced Chemistry of Catalonia (IQAC-CSIC; Barcelona). It is equipped with a laboratory for the development and production of monoclonal antibodies. The laboratory is fully equipped for obtaining, selecting and storing monoclonal antibody producing hybridomas. In addition, the facility has infrastructure for the production of polyclonal antibodies, as well as laboratories for the synthesis of bioconjugates, haptens, the purification of antibodies and the performance of immunoassays. In addition to the above mentioned equipment, the IQAC-CSIC provides animal husbandry facilities and a unit for the synthesis of organic molecules. The equipment consists in an inverted phase contrast microscope with a camera, two Class II laminar flow biological safety cabinets, two CO2 incubators, a bioreactor for hybridoma culture, and tangential filtration unit for purification of the antibodies produced in the culture. Among the items of available equipment it should be highlighted a spotter for selection of high antibody producing cell lines and an automated ELISA microplate washer an ELISA reader, two AKTA Prime Liquid chromatography systems for antibody purification, plus standard equipment (centrifuges, fridges, liquid nitrogen containers, autoclave, baths, and vacuum equipment) and all the necessary routine laboratory apparatus. Cabs also has access to a fully equipped chemistry laboratory for the synthesis of haptens and immunoreagents. The NANBIOSIS Unit 2 works under the ISO9001 certification for standard quality control system QUALITY POLICY FOR THOSE SERVICES IDENTIFIED AS OUTSTANDING, AT LEAST 20% OF THEIR CAPACITY IS OPEN UNDER COMPETITIVE ACCESS. SEE ANNEX 1 OF ACCESS PROTOCOL FOR DETAILS ON % OF OPENNESS FOR EACH SERVICE
05 Nov NANBIOSIS sponsored EBS2025 in Tarragona, showcasing the advances of Units 2 & 29 in antibodies and oligonucleotides for next-gen biosensors. Tarragona, October 2025 — NANBIOSIS proudly participated as an official sponsor of the 5th European Biosensor Symposium (EBS2025), held from 26 to 29 October 2025 in Tarragona. The international event, chaired by Prof. Dr. M. Pilar Marco (IQAC-CSIC / CIBER-BBN and Scientific Director of Unit 2 of NANBIOSIS), brought together hundreds of researchers, engineers and industry leaders to discuss the latest advances in biosensors, nanotechnology, microfluidics, and diagnostic devices. Through its Unit 2 and Unit 29, NANBIOSIS highlighted its key[...] 04 Nov NANBIOSIS held its 2025 networking event in Cáceres to boost collaboration among Units in biomaterials, nanomedicine, and biomedical research. Cáceres, October 2025 — From 22 to 24 October 2025, the Singular Scientific and Technical Infrastructure (ICTS) NANBIOSIS held its annual internal networking event at the Centro de Cirugía de Mínima Invasión Jesús Usón (CCMIJU) in Cáceres, Spain. The event brought together Unit coordinators, researchers, and technical staff from across Spain to foster collaboration, share scientific progress, and explore new opportunities for joint projects in biomedical research, nanomedicine, and biotechnology. A meeting to boost collaboration across NANBIOSIS Units The three-day event[...] 16 Oct NANBIOSIS joins BIOSPAIN 2025 with ISCIII and CIBER, boosting biotech partnerships and showcasing early HTA and ARISTOS innovations. Barcelona, October 2025 — Last week NANBIOSIS took part in BIOSPAIN 2025 (Fira de Barcelona Montjuïc), joining forces at the ISCIII / CIBER stand to showcase our facilities and to deepen collaborations with industry partners, users and strategic allies. Over three intensive days the NANBIOSIS and CIBER representatives held multiple meetings with potential private partners and technology users to accelerate translation of nanomedicine and biomedical technologies. Record edition: numbers that matter BIOSPAIN 2025 closed as the largest edition to date: more than[...] 05 Aug Discover what HPLC is, how it works, and why it’s essential in analytical chemistry and biotechnology. Learn about real applications like LC/MSD iQ integration for antibody purification. What is HPLC? Understanding High-Performance Liquid Chromatography High-Performance Liquid Chromatography (HPLC) is one of the most powerful analytical techniques used in chemistry, biochemistry, and biotechnology. From pharmaceutical quality control to the purification of cutting-edge biotechnological products, HPLC provides high-resolution separation and precise quantification of complex mixtures. Its precision, sensitivity, and versatility have made it indispensable in both research and industrial settings. This article explores how HPLC works, its key components, real-world applications —including[...] 30 Jul Explore modern protein purification methods with a special focus on automated systems like ÄKTA Pure. Learn how advanced chromatography workflows are transforming antibody production, diagnostics, and biotech applications. What is protein purification and why does it matter? Protein purification is a fundamental process in biotechnology, biomedical research, and pharmaceutical production. It involves isolating a specific protein of interest from a complex mixture, such as a cell lysate, while preserving its structure and function. This process is critical because the quality, purity, and yield of proteins directly impact downstream applications such as drug development, diagnostic assays, and therapeutic research. In t[...] 21 May NANBIOSIS will join EBS2025 in Tarragona as organizer and sponsor, with a stand to showcase its services in biosensors and nanobiomedicine. Tarragona, october 2025. NANBIOSIS will be actively participating in the European Biosensors Symposium (EBS) 2025, which will take place from 26th to 29th October in Tarragona, Spain. The event, which brings together leading researchers and innovators in the field of biosensors, provides a platform to discuss the latest scientific and technological advances, promote collaboration, and explore new opportunities for innovation. This year, NANBIOSIS is proud to be part of the organization and will also be present as an officia[...] 21 Jun Barcelona, June 21, 2024 – Prof. Pilar Marco has been appointed as the new head of the Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN) thematic area at the Centro de Investigación Biomédica en Red (CIBER). This prestigious appointment was confirmed during the CIBER Governing Board meeting held on June 20, 2024. Prof. Marco succeeds Ramón Martínez, bringing a wealth of expertise and a distinguished track record in biomedical research for more than a decade. Prof. Marco is a research professor at the Consejo Superior de Investigaciones Científicas (CSIC), specifically at the Institute of Advanced Chemistry of Catalonia (IQAC) in Barcelona. Additionally, s[...] 28 Feb Researchers from IQAC-CSIC advance towards faster detection and treatment of cystic fibrosis and rare respiratory diseases, improving patient outcomes. 28 February 2024, IQAC-CSIC (Barcelona) Cystic Fibrosis (CF) is a progressive autosomal recessive disease. It is caused by a mutation in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, disrupting its exocrine activity. While CF affects various organs, its impact on the lungs is particularly severe. This disease leads to the accumulation of thick, sticky mucus, obstructing airways and trapping bacteria, resulting in significant infections and extensive lung damage. Consequently, individuals with CF are highly susceptible to respiratory[...]
U2. Custom Antibody Service (CAbS)



Description
Services
Equipments
Active projects
Other projects
Ref
Title
Funding Organism
Unit Role
SAF2015-67476-R
Immunochemical Strategies of Diagnosis and Therapy based on Quorum Sensing (ImmunoQS)
Ministerio de Economía y Competitividad
Participant
PIE1400061
Molecular links between diabetes and neurodegenerative diseases
ISCIII
Oberver
2014SGR1484
Consolidated Research Group
Generalitat de Catalunya
Participant
FP7-614168
Real time monitoring of SEA contaminants by an autonomous Lab-on-a-Chip biosensor (SEA-on-a-CHIP)
European Commission
Oberver
CI16-00031 Caixa Impulse
A new approach for the detection of Pseudomonas aeruginosa
CaixaBank
Participant
MSCA-ITN2015-675412
New Diagnostics for Infectious Diseases
European Commission
Participant
TECCTP15-1-0011
Ajuda acreditació Tecnio del grup Nb4D
ACCIÓ: Generalitat de Catalunya
Others
Publications
2016
News U2

NANBIOSIS Showcases Biosensor Innovation as Sponsor of EBS2025 in Tarragona

NANBIOSIS Strengthens Internal Collaboration at 2025 Networking Event in Cáceres

NANBIOSIS at BIOSPAIN 2025: Strengthening public-private bridges for translational nanomedicine

HPLC: What It Is, How It Works, and Its Applications in Modern Biotech

Protein Purification Methods: Advanced Techniques and Automation with ÄKTA Pure

NANBIOSIS to participate in the new edition of the European Biosensors Symposium 2025

Prof. Pilar Marco takes helm of CIBER-BBN: Leading the future of Bioengineering, Biomaterials, and Nanomedicine

The fight against rare respiratory diseases: New hope in detection and treatment
























