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A Minimally Invasive Microsensor Specially Designed for Simultaneous Dissolved Oxygen and pH Biofilm Profiling

Ana Moya, Xavi Illa, Rosa Villa and Gemma Gabriel, researchers of the Biomedical Application’s Group (GAB) of CIBER-BBN and the Microelectronics Institute of Barcelona, which main interests are the design and fabrication of Micro and Nano Systems for Biomedical Applications, have recently published, in collaboration with other authors an article in the Special Issue Advanced Electrochemical Sensors and Environmental Monitoring

The authors thank in the Acknowledgements the participation of the ICTS NANBIOSIS U8 Micro– Nano Technology Unit of the CIBER in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) at the IMB -CNM (CSIC)

The work reports the development of a novel multi-analyte microsensor based on MEMS technologies for simultaneous monitoring of DO and pH. Results showed the capacity of microsensors to quantify concentration gradients of di erent species within biofilms. In addition, the possibility of integrating two microsensors, specially designed to obtain a seven-point profile in a single measurement, introduced in this paper for the first time, clearly simplifies the equipment and the procedure necessary to record concentration profiles within biofilms. Critical future prospects have been established

Article:

Xavier Guimerà , Ana Moya, Antonio David Dorado, Xavi Illa, Rosa Villa, David Gabriel, Xavier Gamisans and Gemma Gabriel. A Minimally Invasive Microsensor Specially Designed for Simultaneous Dissolved Oxygen and pH Biofilm Profiling Sensors 2019, 19(21), 747; https://doi.org/10.3390/s19214747

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NANBIOSIS Scientific Director, Jaume Veciana, coauthor of an article highlighted in Chemistry Views

Jaume Veciana, Scientific Director of NANBIOSIS is coauthor of an article chosen to be highlighted on the ChemistryViews newsletter: “Organic Free Radicals as Circularly Polarized Luminescence Emitters”, published in Angewandte Chemie International Edition, and is about the intrinsic chiral emission of enantiometric organic free radicals.

The short news about the paper is entitled “Circulary Polarized Light from Organic Radicals” is available here. 

Circularly polarized luminescence (CPL) can occur when a luminescent compound has a chiral structure. Organometallic structures are leading in CPL activity. However, purely organic CPL emitters are promising alternatives in several applications where low toxicity is important
(i.e., bioimaging).

Jaume Veciana (Institut de Ciéncia de Materials de Barcelona (ICMAB), Spain), Araceli G. Campaña (University of Granada, Spain) and colleagues have found a new approach for the optimization of organic emitters with intrinsic chirality. In particular, tris(2,4,6-trichlorophenyl)methyl (TTM) and perchlorotriphenylmethyl (PTM) radicals, which both have a chiral propeller-like shape, were used. In addition to their chirality, these materials are magnetically active. They are also easy to modify in order to optimize their properties.

The team separated the two racemic compounds into their enantiomers using chiral stationary phase high-performance liquid chromatography (HPLC). The CPL spectra of the four resulting fractions (examples pictured) were recorded and the researchers found highly efficient chiral emission for both pairs of enantiomers. According to the researchers, this is the first time results about the intrinsic chiral emission from enantiomeric organic free radicals have been reported. The work might be a starting point for the development of improved chiral organic radical emitters.

Reference article:Organic Free Radicals as Circularly Polarized Luminescence Emitters
Paula Mayorga Burrezo, Vicente G. Jiménez, Davide Blasi, Imma Ratera, Araceli G. Campaña, Jaume Veciana,
Angew. Chem. Int. Ed.2019.
https://doi.org/10.1002/anie.201909398

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Unit 16 of NANBIOSIS will expand its capabilities with cofinancing of FEDER funds

On October 25, the Monitoring Commission of the agreement signed on July 15 was established by the Ministry of Economy, Industry and Competitiveness and the University of Extremadura for the acquisition of new equipment that will expand the capabilities of Unit 16 of NANBIOSIS.

One of the 26 Units that constitute NANBIOSIS is Unit 16 “Unit of Surface Characterization and Calorimetry” of CIBER-BBN and the University of Extremadura. The application of this FEDER cofinancing will allow the expansion of the capabilities of this unit for the chemical, physicochemical, and topographic characterization of surfaces, improving the competences in mass spectrometry by time of flight of secondary ions (TOF-SIMS), photoelectron spectroscopy (XPS) and extending them to the profilometry goniometry and goniometry. The requested equipment will be located on the Badajoz campus of the University of Extremadura, where Unit 16 of NANBIOSIS is located.

The total budget of the project is € 1,380,000, 80% of which are co-financed with funds from the European Regional Development Fund (FEDER) corresponding to the Spanish Multi-Regional Operational Program 2014-2020, allocated to the General Secretariat for Coordination of Scientific Policy of the Ministry of Science, Innovation and Universities destined to finance projects and actions related to infrastructures included in the current ICTS Map. The remaining 20% ​​is contributed by the Junta de Extremadura.

Further information here

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New inside backcober by researchers of NANBIOSIS U9

Researchers of NANBIOSIS U9 Synthesis of Nanoparticles Unit Ignacio Julian, José L. Hueso, Reyes Mallada and Jesús Santamaría, are co-authors of an article with inside backcover recently published by the scientific magazine Catalysis, Science and Tecnology.

The synthesis of the materials has been performed at the Platform of Production of Biomaterials and Nanoparticles of the NANBIOSIS ICTS, more specifically at the Nanoparticle Synthesis Unit 9 of the CIBER in BioEngineering, Biomaterials & Nanomedicine (CIBER-BBN)

Article: Polyoxometalates as alternative Mo precursors for methane dehydroaromatization on Mo/ZSM-5 and Mo/MCM-22 catalysts. Julián I, Hueso J.L, Lara N, Solé-Daurá A, Poblet J,M, Mitchell S.G, MalladaR, Santamaría J.Catal. Sci. Technol., 2019, 9, 5927
DOI: 10.1039/C9CY01490J 

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CCMIJU: Online Course on INTRODUCTION TO RESEARCH AND LABORATORY TECHNIQUES IN BIOCIENCES

During de dates Nov. 18 -30, 2019 will take place de course on line on Introduction to Research and Laboratory Techniques in Biociences, under the direction of NANBIOSIS U14 Cell Therapy Unit led by Javier García Casado Scientific Director of the Unit and Francisco M. Sánchez Margallo Scientific Director of CCMIJU and Deputy Scientific Director of NANBIOSIS.

For further information: Online Course on INTRODUCTION TO RESEARCH AND LABORATORY TECHNIQUES IN BIOCIENCES

Matriculación online
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Workshop on “ETHICAL ASPECTS OF RESEARCH”

The Nanobiotechnology for Diagnostics group (Nb4D) of CIBER-BBN and IQAC-CSIC, (coordinator of NANBIOSIS U2 Custom Antibody Service (CAbS)), led by Prof. Mª Pilar Marco, is organizing a workshop on “Ethical aspects of research” netx 18th November 2019, at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC). 

There will be three sessions given by experts from this topic area.

  • TECHNOLOGICAL ADVANCES VERSUS ETHICS by Dr. José Ignacio Latorre
  • ANIMAL TESTING by Dr. Lluís Montoliu
  • CLINICAL SAMPLES, BIOBANKS AND OTHER ASPECTS IN CLINICAL PRACTICE by Dr. Pieter Moons

A Certificate of Attendance will be issued for each participant.

This workshop is FREE but has LIMITED SPACE. To  register, fill in the form by 10th November 2019: https://bit.ly/2VI5W3j

Venue: Salón de Actos, CID-CSIC C/Jordi Girona 18-36. Barcelona. Monday, November 18, 2019, 9:30 h

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